Velindre NHS Trust

20 Updates on Magnetic Resonance Imaging assessment of tumour MicrOStructure in GlioblastomA: A cross-sectional study (The MIMOSA Study)

Abstract The MIMOSA (Magnetic Resonance Imaging assessment of tumour MicrOStructure in GlioblastomA) study is recruiting patients with a presumed diagnosis of glioblastoma (GBM) pre-operatively to receive advanced diffusion-weighted magnetic-resonance-imaging (DW-MRI) using the C...

108 Interpretable Radiomics-Based Prediction of IDH Status in Glioma

Abstract Introduction Glioblastoma (GBM) is the most frequent primary brain tumour. The 2021 WHO CNS Tumour Classification highlights the importance of IDH mutation status for accurate diagnosis and treatment. However, biopsies are invasive and may not fully capture tumour hetero...

44 UK radiotherapy practice in volume delineation–data from the APPROACH trial (ISRCTN:1339049) radiotherapy quality assurance (RTQA) programme benchmark outlining case

Abstract Introduction Interobserver variation in radiotherapy contouring can affect protocol compliance and the robustness of clinical trial outcomes. The APPROACH (Analysis of Proton vs Photon Radiotherapy in Oligodendroglioma and Assessments of Cognitive Health) trial protocol...

90 Developing Patient-Focused Outcomes for Routine Clinical Care in Glioma: A Synthesis of Qualitative Evidence from the COMBaT Study

Abstract Introduction There is a critical need to identify and routinely measure the outcomes that matter most to people living with glioma. Care needs in this population are complex and variable, yet current clinical practice lacks consistent, systematic approaches to assessing...