Vasile Goldis Western University of Arad

Association Between Graves’ Disease and the Risk of Thyroid Carcinoma: The Role of Clinical, Metabolic, Hormonal, Immunological, and Ultrasound Biomarkers

Background: The relationship between Graves’ disease (GD) and thyroid carcinoma (TC) remains controversial, particularly regarding the predictive value of metabolic, hormonal, immunological, and ultrasound biomarkers. We performed a systematic review and meta-analysis to evaluate...

Pulmonary Reserve and Respiratory Recovery After Cardiac Surgery: Insights from Preoperative Spirometric Phenotyping

Background: Postoperative respiratory dysfunction remains a frequent complication after cardiac surgery, yet the influence of preoperative pulmonary reserve on postoperative respiratory recovery remains incompletely understood. We investigated whether preoperative spirometric phe...

Association of Serum 25-Hydroxyvitamin D, Inflammatory, and Metabolic Biomarkers with Non-Proliferative Diabetic Retinopathy in Type 2 Diabetes Mellitus: A Cross-Sectional Study

Background: Non-proliferative diabetic retinopathy (NPDR) is a common microvascular complication of type 2 diabetes mellitus (T2DM) associated with chronic inflammation, metabolic dysregulation, and multiple interacting systemic factors. This study evaluated the associations of i...

EUS-guided and US-guided percutaneous splenic biopsy: a systematic review and meta-analysis of separately pooled diagnostic and safety outcomes

Ultrasound (US)-guided percutaneous splenic biopsy has been widely used to evaluate focal or diffuse splenic lesions and has shown promising efficacy and safety. Endoscopic ultrasound (EUS)-guided biopsy has emerged as an alternative approach for tissue acquisition from splenic l...

Thermal analysis in pharmaceutical sciences: a critical narrative review with focus on drug–excipient interactions

Abstract Thermal analysis has become an indispensable component of the modern pharmaceutical preformulation toolbox, providing rapid, low-mass, and information-rich answers to questions of identity, purity, polymorphism, thermal stability, and—most critically—drug–excipient compa...