Institution
VA Northeast Ohio Healthcare System
UShealthcare
Recent research
- BiologyOpen access
Adaptive landscape of the metallo-β-lactamase NDM-1 to emerging β-lactam-based therapies
ABSTRACT The New Delhi metallo-β-lactamase (NDM) is a major determinant of carbapenem resistance. This has prompted the development of novel therapeutic strategies to treat NDM producers. Since these therapies impose new selective pressures, their clinical deployment may favor ND...