VA Greater Los Angeles Healthcare System

Scoping review in facilitating occupational participation using technology for neurorehabilitation

Date presented: April 25, 2026 Primary Author and Speaker: Joahnes Gatdula, gareth22m@gmail.com

Effect of Age on Physical Function Improvement in Older Veterans Enrolled in the Gerofit Exercise Program

Background/Objectives: Aging is associated with declines in strength, balance, and mobility that contribute to falls, disability, and loss of independence. While exercise interventions improve physical function, limited data exist on community-dwelling adults aged 90 years and ol...

A CCL21 gene-modified dendritic cell vaccine combined with pembrolizumab in advanced non-small cell lung cancer: a phase I trial

Abstract Immune checkpoint inhibitors (ICIs) have transformed treatment for non-small cell lung cancer (NSCLC), but resistance to these therapies is common. We report here results from a phase I trial combining intratumoral injection of a CCL21-expressing dendritic cell (CCL21-DC...

Moderators of the Effects of Telehealth Mindfulness-based Interventions for Chronic Pain

OBJECTIVES: Little is known about who benefits most from Mindfulness-Based Interventions (MBIs), and whether certain groups differentially benefit from different types of MBI formats (group-based versus non-group based). The present study uses data from a three-arm randomized con...

Radiology considerations for the PREMIUM study: a multicenter randomized controlled trial of abbreviated MRI versus ultrasound for liver cancer screening in cirrhosis

Abstract This paper describes the rationale and radiology considerations in the implementation of the Preventing Liver Cancer Mortality through Imaging with Ultrasound versus MRI (PREMIUM) study. PREMIUM is a multicenter, randomized controlled trial sponsored by the Department of...

Get With The Guidelines–Heart Failure Hospital Participation and Its Association With Guideline-Directed Medical Therapy and Outcomes

Abstract Purpose Despite strong evidence, real-world adoption of guideline-directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF) remains suboptimal. The Get With The Guidelines–Heart Failure (GWTG-HF) program was designed to close gaps in care....

Associations Between Combat Exposure, Traumatic Brain Injury, and Sleep Outcomes Among Post-9/11 Veterans

OBJECTIVE: The authors examined the relationship between veterans' combat experiences and multiple dimensions of sleep health and how traumatic brain injury (TBI) history may modulate these relationships. METHODS: Participants were 17,812 post-9/11 veterans (mean±SD age=46.6±10.8...

Sucralose Alters Gut Microbiota, Intestinal Metabolites, and Epithelial Serotonergic Responses to Visceral Stimulation in Mice Exposed to Chronic Restraint Stress

Background/Objectives: Dietary modifiers of the gut ecosystem may influence intestinal and host responses associated with psychological stress. However, it remains unclear whether sucralose, a widely consumed non-nutritive sweetener, alters host–microbiota interactions following...

Lipids in endothelial-to-mesenchymal transition

Purpose of review Endothelial-to-mesenchymal transition (EndMT) has been implicated in the development of cardiovascular disease, including atherosclerosis. EndMT is a complex continuum with multiple involved pathways, each with different pathophysiologic implications depending o...

Chronic oral exposure to didecyldimethylammonium chloride induces region-specific intestinal dysfunction and gut microbiota remodeling in mice

bstract Didecyldimethylammonium chloride (DDAC) is a widely used quaternary ammonium disinfectant, but its effects on intestinal physiology following chronic oral exposure remain poorly understood. Here, we investigated the impact of chronic dietary DDAC exposure on intestinal fu...