Usmanu Danfodiyo University

Targeting Alzheimer’s disease pathways with Caralluma dalzielii: behavioural, biochemical, and molecular evidence from a transgenic Drosophila melanogaster model

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with limited disease-modifying therapies, necessitating the exploration of novel therapeutic agents. Caralluma dalzielii, a medicinal plant traditionally used for neurological disorders, has not previously been...

PredKlebAMR: A machine learning framework prioritizing sensitivity in Klebsiella pneumoniae resistance profiling

The global increase in carbapenem-resistant Klebsiella pneumoniae (CRKP) has undoubtedly changed the management of infectious diseases. Meropenem resistance in K. pneumoniae is a response to bacterial strategies, these includes production of carbapenemases (KPC, NDM, OXA-48), a r...

A cross-sectional study of hepatitis B vaccination coverage and occupational risk exposure among health science students in a Nigerian University

Abstract Introduction Despite the presence of a safe and effective vaccine for hepatitis B virus (HBV), health science students remain at significant risk for infection. This study assessed HBV vaccination coverage, awareness, and associated factors among health science students...

Methodological Evaluation and Panel-Data Estimation of Industrial Machinery Fleet System Reliability in Nigeria, 2000–2026

{ "background": "Industrial machinery fleet reliability is a critical determinant of productivity and economic output in developing economies. However, systematic, longitudinal assessments of fleet system performance in such contexts are scarce, limiting evidence-based maintenanc...

Methodological Evaluation and Panel-Data Estimation of Industrial Machinery Fleet System Reliability in Nigeria, 2000–2026

{ "background": "Industrial machinery fleet reliability is a critical determinant of productivity and economic output in developing economies. However, systematic, longitudinal assessments of fleet system performance in such contexts are scarce, limiting evidence-based maintenanc...

Exploring the Determinant of Financial Inclusion in Nigeria: The Role of Digital Financial Access and Socio-Economic Factors

This study investigates the determinants of financial inclusion in Nigeria, with particular emphasis on digital access and usage. Using individual-level data from the 2025 Global Findex Database and survey-weighted logistic regression, the study examines how socio-economic charac...

Socio-demographic characteristics and awareness of risk factors of severe acute malnutrition among parents of children admitted in stabilization centres in Northern Nigeria: A multi-centre observational study

Objectives: The study aims to determine socio-demographic characteristics and assess awareness of risk factors of severe acute malnutrition (SAM) among parents of children admitted to stabilisation centres in Northern Nigeria. Material and Methods: A descriptive cross-sectional s...

Hemodynamic and Myocardial Workload Responses to Cold Pressor Stress in Apparently Healthy Young Adults

Abstract Background:The Cold Pressor Test (CPT) is a validated experimental model used to assess autonomic cardiovascular reactivity. It induces acute sympathetic stimulation resulting in measurable hemodynamic changes. Objective:To evaluate cardiovascular responses to CPT in app...

Hemodynamic and Myocardial Workload Responses to Cold Pressor Stress in Apparently Healthy Young Adults

Abstract Background:The Cold Pressor Test (CPT) is a validated experimental model used to assess autonomic cardiovascular reactivity. It induces acute sympathetic stimulation resulting in measurable hemodynamic changes. Objective:To evaluate cardiovascular responses to CPT in app...

Retrocaval Ureter in a 7-Year-Old Girl Causing Symptomatic Unilateral Hydronephrosis- A Rare Case Report

Retrocaval ureter is a rare congenital anomaly in which the proximal ureter courses posterior to the inferior vena cava (IVC), potentially causing obstruction. It predominantly affects males (M: F ratio 4:1) and usually presents in the third or fourth decade of life. Presentation...