Uniwersytecki Szpital Dziecięcy

Ambroxol in Gaucher disease and GBA1-related Parkinson disease: an updated systematic review

Abstract Background Ambroxol (ABX) is a central nervous system (CNS)-penetrant compound that can increase glucocerebrosidase activity and has been investigated in Gaucher disease (GD) and GBA1 -related Parkinson disease ( GBA1 -PD). Methods This PRISMA 2020 systematic review and...

Urinary creatinine in very low gestational age neonates: importance for interpretation of creatinine-normalized urinary amino acids

OBJECTIVES: Urinary creatinine concentration is widely used to normalize urinary analytes. However, its reliability in preterm neonates remains uncertain. This study aimed to evaluate urinary creatinine concentrations in very low gestational age (VLGA) neonates and assess its imp...

Development and preliminary evaluation of a digital platform for surgical anatomy education

The transition from foundational anatomy education to applied surgical anatomy remains a persistent challenge in medical and surgical training. This study describes the development and preliminary evaluation of Anatomy Unlocked , a mobile-first, clinically oriented digital anatom...