University Town of Shenzhen

Frequency-specific structure-function decoupling underlies core symptoms in schizophrenia

A major challenge in schizophrenia is its clinical heterogeneity, which has obstructed biomarker identification. Recent research indicates that frequency-specific structural eigenmodes, which govern distinct spatiotemporal propagation patterns, are linked to the functions of unim...

Pectin–Protein Complexes: A Design‐Oriented Platform for Tailoring Food Texture Modification

ABSTRACT Pectin–protein complexes have emerged as promising functional ingredients in texture‐modified foods (TMF) due to their multifunctional roles in gelation, emulsification, and water retention. These properties enable the design of customized textures for applications such...

Programmable RNA targeting with clustered regularly interspaced short palindromic repeats (CRISPR) effector Cas7-11 in zebrafish embryos and mammalian cells

<title>Abstract</title> <bold>Background</bold> The CRISPR/Cas7-11 system is a recently characterized RNA editing tool that exhibits low toxicity, minimal off-target effects, and reduced collateral RNA cleavage compared with existing methods. Although zebrafish and human embryoni...

The Effects of Expressive Arts Therapy on Emotion Regulation and Aggression in Violent Offenders: A Randomized Controlled Trial

Violent crime is a widely recognized public health concern. According to emotion regulation theory, aggressive behavior in violent offenders is linked to maladaptive emotion regulation strategies. However, few studies have explored interventions targeting emotional factors to red...

Research on the Online Diagnosis Method for Heating Types of Composite Insulator

ABSTRACT In response to the current challenge of accurately determining the specific heating status of composite insulators with localised temperature rise using infrared detection technology, this paper proposes a novel diagnostic method. This method involves applying a disturba...

Apoptosis of Mdm2-deficient osteocytes enhances osteogenesis through TRPM8-enriched apoptotic vesicles

During homeostasis, osteocyte apoptosis is typically associated with bone loss through enhanced osteoclast recruitment and bone resorption. However, whether apoptotic osteocytes also regulate bone formation remains elusive. Here we report that conditional deletion of Mdm2, an E3...

Extracting structure–activity relationships from patents with large language models

Abstract Background Persistent clinical failures in drug development arise from multiple factors, including imbalanced molecular properties, underscoring the need for systematic structure–activity relationship analysis to link structural modifications with optimized efficacy, sel...

A Self‐Adaptive Multipole Receiver for Interoperable Wireless Electric Vehicle Charging with Enhanced Misalignment Tolerance

ABSTRACT In wireless power transfer (WPT) for electric vehicles (EVs), interoperability issues often arise when the transmitter and receivers are of different types such as Q and DD coils. Misalignment between coils is inevitable in practical applications, leading to a sharp decl...