University of York

Breast Cancer Knowledge and Screening Barriers Among Female University Students of Pakistan

Breast cancer is a leading public health concern among low- and middle-income countries, primarily due to inadequate knowledge and lack of early detection practices. This study aimed to assess knowledge about the signs and symptoms, risk factors, and screening procedures for brea...

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications

ABSTRACT Cysteine thioaldehydes are putative intermediates in sulfatase‐maturing enzyme catalysis and in the biosynthesis of penicillin, coenzyme A and families of ribosomally synthesized and posttranslationally modified peptides (RiPPs). Norrish type‐II photolysis of phenacylsul...

A conserved grain-associated immunosuppressive niche in Sudanese patients with mycetoma

Abstract Mycetoma is a neglected tropical disease caused by various bacterial and fungal pathogens that has a significant health impact across a broad geographically defined “mycetoma belt” spanning South America, Africa and Asia. Histologically, mycetoma is characterised by inva...

Fine Tuning of Ag3PO4/g-C3N4 Hybrid Nanostructure Catalyst for Natural Sunlight-Assisted Cationic Dye Neutralization

Photocatalysis is a promising route for the environmentally friendly destruction of organic pollutants and recycling the polluted water in industrial contexts for future environmental challenges. In this novel research work, the coupling of definite proportions of silver phosphat...

Conservation and divergence within the Arabidopsis TPL/TPR corepressor family

Abstract The TOPLESS (TPL) and TOPLESS-RELATED (TPR1–TPR4) corepressors, collectively the Arabidopsis TPX family, are recruited by client proteins to regulate nearly every major plant regulatory program. Here, we dissect the conservation and divergence between paralogs using a co...

Mobility and Roman Britannia

Abstract This article reviews the evidence for mobility within, and into, the Roman province of Britannia, assesses the current state of the field and sets out how current approaches should be developed and improved. Mobility was foundational to the Roman empire and its provinces...

Barriers to the uptake of cervical cancer screening methods in Low- and Middle-Income Countries (LMICs) – a scoping review using framework thematic analysis

Abstract Background Cervical cancer remains a major cause of preventable death among women in low- and middle-income countries (LMICs). Despite the availability of effective screening, uptake remains low. Existing reviews have not fully captured the socio-cultural and behavioural...

Sustainable Synthesisof Diamide Solvents from SuccinicAnhydride under Microwave Conditions for the Production of Graphenevia Liquid-Phase Exfoliation

Abstract Liquid-phase exfoliation (LPE) is a viable method for the large-scale production of two-dimensional (2D) graphene; however, toxic solvents must be replaced. The microwave synthesis of sustainable succindiamide solvents, namely N,N′-diethyl-N,N′-dibutylsuccindiamide (EBSA...

Aflibercept 8 mg in neovascular age-related macular degeneration and diabetic macular oedema: Translating clinical trials into clinical practice

Abstract Provide expert-informed guidance on the integration of aflibercept 8 mg into routine clinical care for patients with neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO), based on clinical trial and real-world evidence. Sixteen retina spe...

Meta-analysis and network meta-analysis of time-to-event outcomes with non-proportional hazards: a Bayesian time-varying hazard ratio approach

Abstract Background Meta-analyses of time-to-event (TTE) outcomes, particularly in Health Technology Assessment (HTA), commonly use a hazard ratio (HR) scale. However, non-proportional hazards in included trials create difficulties. Existing methods are either too complex or not...

Prosociality in times of war: Shared moral positions foster prosociality across national borders

In times of severe intergroup conflict, cross-national interactions are shaped by social categorization along national and moral dimensions. Yet, little is known about how these co-occurring identities jointly shape prosocial behavior. Across three studies (total N = 1178), we ex...

Promoting smoking cessation and preventing relapse to tobacco use following a smokefree mental health in‐patient stay: A multi‐centre randomised controlled feasibility study

Abstract Aims This study assessed the feasibility and acceptability of a new theory‐ and evidence‐based intervention designed to prevent return to pre‐admission smoking behaviours after discharge from a smokefree mental health in‐patient setting in the United Kingdom (UK). Design...

How do visual and conceptual factors predict the object content in typical scene drawings?

Imagine you draw a typical bedroom, your choice of objects is likely to depend on visual occurrence statistics (i.e. the objects present in previously encountered bedrooms) and semantic relations between objects and scenes (i.e. the semantic relationship between the bedroom and i...