University of Veterinary Medicine

Preclinical evaluation of naturally derived viral nucleic acids in combination cancer immunotherapy

Abstract Effective cancer immunotherapy often requires coordinated activation of innate and adaptive immune responses. While the previous studies have primarily focused on whole oncolytic viruses, synthetic or engineered viral nucleic acids, or inactivated viral particles, the th...

Combined Marbofloxacin-Geraniol-Tris-EDTA Exposure Delays Marbofloxacin Resistance Escalation in Pseudomonas aeruginosa While Early Genomic Changes Remain Limited

Background: Pseudomonas aeruginosa combines intrinsic resistance, adaptive plasticity, and biofilm formation, making treatment failure common in veterinary and human medicine. We examined whether geraniol and Tris-ethylenediaminetetraacetic acid (Tris-EDTA) modulate marbofloxacin...