University of Vermont

A community-validated tool for clinical outcome calculation in multiple sclerosis: Consensus development and scenario-specific recommendations

Background: Reproducibility and comparability of disability outcomes remain major challenges in multiple sclerosis (MS) research. Definitions of disability progression vary widely across studies, and calculation criteria are often insufficiently documented to enable replication....

Genome-wide identification and tissue-specific profiling of microRNAs in lentil (Lens culinaris Medik.)

MicroRNAs (miRNAs) are key post-transcriptional regulators involved in plant development, metabolism, and stress adaptation. Despite the agronomic importance of lentil ( Lens culinaris Medik.), its miRNA landscape remains relatively underexplored. This study aimed to generate a c...

Impact of Charlson Comorbidity Index conditions on one-year survival in patients with breast cancer: a Danish population-based cohort study

Breast cancer is the most frequently diagnosed malignancy in women. The Charlson Comorbidity Index (CCI) is a widely used tool for quantifying multimorbidity. As the population ages, breast cancer incidence and comorbidity prevalence are expected to grow. We therefore investigate...

Implementation of a pilot online educational program to identify paramagnetic rim lesions

Background: Paramagnetic rim lesions are a highly specific magnetic resonance imaging biomarker for multiple sclerosis now incorporated into the 2024 McDonald Criteria. However, paramagnetic rim lesion identification remains underutilized in clinical practice. This study evaluate...

P1.199. Preoperative Frailty Testing for Esophagectomy: Stair-Climb Time as the Strongest Predictor of Major Complications

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Esophageal cancer is increasingly common in an aging population. Esophagectomy remains a cornerstone of treatment but carries substantial perioperative risk. Ac...

A Bayesian approach to postfire debris-flow probability modeling for southern California, United States

Background Intense rainfall on steep, burned landscapes can initiate postfire debris flows (PFDFs). Watershed-scale estimates of PFDF probability in response to a given rainfall intensity are beneficial for assessing PFDF hazards, including prioritizing areas for hazard mitigatio...

Role of the School Nurse in Providing School Health Services: Policy Statement

School nursing has evolved into an essential field bridging health care and education. School nurses play multifaceted roles, addressing direct care, care coordination, public health, leadership, and quality improvement. They manage communicable diseases, chronic conditions, ment...

Physical activity reduces mental health burden in adults with a history of adverse childhood experiences

BACKGROUND: Adverse childhood experiences (ACES) are associated with health issues that can persist into adulthood including mental disorders, behavioral problems, and suicide. Physical activity (PA) is a potential tool in response to these burdens as it is profoundly beneficial...

Controlled flight of high-thrust ultralight ion-propelled microrobot with integrated sensing

Ion wind technology holds potential for the miniaturization of flying microrobots, generating thrust without mechanical moving parts, enabling simplified and light designs free from high-frequency actuators. Nevertheless, two fundamental challenges have limited its practical impl...

The Zooplankton International Geospatial dataset: A global repository of spatiotemporal freshwater zooplankton community composition data from lakes and reservoirs to support ecological research

Abstract Zooplankton transfer substantial energy in aquatic food webs and are used as indicators of environmental change. Syntheses of zooplankton community dynamics globally require datasets that span a wide range of environmental gradients; however, these datasets are limited d...

Impaired but now diagnosable: Combining analytic frameworks for incorporating symptom weighting in the classification of full‐threshold and subthreshold posttraumatic stress disorder

Abstract Individuals with subthreshold posttraumatic stress disorder (PTSD) often experience significant impairment yet face barriers to care (e.g., insurance denials and exclusion from clinical trials) due to strict Diagnostic and Statistical Manual of Mental Disorders ( DSM )–b...

Integrated Molecular Docking and Molecular Dynamics Approaches Reveal Potential Antimicrobial Metabolites from Echinoderms, Holothuria scabra

The rapid emergence of multidrug-resistant microbial pathogens has created an urgent need for new antimicrobial agents. Marine organisms are a rich source of structurally diverse bioactive metabolites with therapeutic potential, and the sea cucumber H. scabra contains numerous se...