University of Shizuoka

Organellar Genome Analysis of the Red Alga Acrosorium flabellatum (Rhodophyta, Ceramiales, Delesseriaceae): Evidence of Gene Duplication and Group II Intron in cox1 Gene

Mitochondrial genomes (mitogenome) offer important information about evolutionary history, genomic diversity, and structural dynamics of Rhodophytes. The complete mitochondrial genome of Acrosorium flabellatum Yamada, 1930 (Delesseriaceae, Ceramiales), is reported in this study....

Ontogenetic Changes in Mercury and Stable Isotope Ratios in Pacific White-Sided Dolphins (Lagenorhynchus obliquidens) Stranded in Hokkaido, Japan: Comparison with Harbour and Dall’s Porpoises

The Pacific white-sided dolphin (PWD) is a small cetacean that is hunted for human consumption in central Japan, and is frequently stranded on the coast of Hokkaido, northern Japan. However, little information is available on the Hg contamination and ecology of PWDs. We investiga...

Complete genome sequence of Methylorubrum sp. strain 263, a light-driven methylotrophic bacterium

sp. strain 263 is a pink-pigmented facultative methylotrophic bacterium showing light dependence for methylotrophic growth. Here, we report the complete genome sequence of strain 263 consisting of a chromosome (5,298,893 bp) and a circular plasmid (44,302 bp).

Triangulating Evidence on Serum Uric Acid and Cancer Risk: Consistent Inverse Associations With Lung Cancer

ABSTRACT We examined the association between serum uric acid (UA) levels and cancer incidence through a conventional observational and two‐sample Mendelian randomization (MR) study in the same population (triangulation). We followed 13,695 individuals aged 35–69 years for cancer...

Gut microbial phenol impairs energy metabolism and promotes sarcopenic obesity-like phenotypes in mice

Abstract Gut microbial phenol has been recognized as a uremic toxin associated with chronic kidney disease; however, its effects under preclinical conditions remain unclear. In this study, we established a mouse model with increased endogenous phenol production using a tyrosine-r...

Clinical applicability of cystatin C-based renal function assessment and HPLC-based therapeutic drug monitoring for predicting cefepime overexposure

Abstract Background Cefepime (CFPM)-associated neurotoxicity is linked to elevated plasma concentrations, particularly in patients with impaired renal function. Although cystatin C-based estimated glomerular filtration rate (eGFRcys) has been proposed as a potentially superior ma...

Association of medical visit frequency with cardiovascular events and mortality in patients with dyslipidaemia: a cohort study using a Japanese claims database

Abstract Background Dyslipidaemia is a major risk factor for cardiovascular and cerebrovascular diseases; however, the optimal frequency of medical visits remains unclear. Objective To examine whether medical visit frequency is associated with the incidence of cardiac events, cer...

Standardization of shotgun metagenomics parameters for pks-positive enterobacteria detection in human fecal samples: Receiver operating characteristic analysis using polymerase chain reaction as reference standard

Enterobacteria harboring the polyketide synthase ( pks ) island ( clbA – clbS ), which encodes colibactin ( pks⁺ enterobacteria), is a putative risk factor for colorectal cancer. Polymerase chain reaction (PCR) is the current standard for detection. Primer-independent shotgun met...