University of Puerto Rico-Mayaguez

HIV-1 Tat Forms a Dissociable Complex with 7SK snRNP and Exhibits Clade Differences in Reversing the Sequestration of P-TEFb

Recent efforts to employ ectopic Tat as a latency-reversal strategy can benefit from the identification of Tat variants with more efficient transactivation activity. Tat primarily serves as a recruiter of the host transcription elongation factor P-TEFb to proviral HIV to stimulat...

Crystallizationfor Manufacturing in Microgravity;Are We There Yet?

Abstract Crystallization in microgravity has been extensively investigated because of its potential to enhance crystal quality compared to terrestrial conditions. While early efforts were primarily directed toward single-crystal growth for structural studies, increasing attention...

A Review ofAmmonia (NH3) Adsorption inPorous Solids

Abstract Ammonia (NH3) plays a crucial role in the agricultural sector as a fertilizer and is a dense hydrogen carrier that offers a potential renewable and carbon-free energy source. These significant advantages necessitate the development of efficient NH3 synthesis and separati...

DNA methylation modulation by 5-Azacytidine regulates EMT markers and reduces invasiveness in docetaxel-resistant prostate cancer cells

<title>Abstract</title> <bold>Background:</bold> Metastatic castration-resistant prostate cancer (mCRPC) is associated with poor prognosis and high mortality, largely due to the emergence of androgen and chemotherapy resistance. Resistance to docetaxel occurs in nearly 50% of pat...

Measuring Ocean Surface Waves

Abstract Propagating waves on the ocean surface can be represented as a stochastic process whose statistics are characterized by a spectrum. This paper reviews methods for measuring the wave spectrum and related quantities. Observations begin by sensing fluid dynamical properties...