University of Palermo

P1.105. Epithelial–Mesenchymal Plasticity Underlies Adaptive Resistance to FLOT Chemotherapy in Esophageal Adenocarcinoma

Abstract Topic Esophageal Cancer: Molecular Biology/Pathology Background Resistance to perioperative FLOT chemotherapy remains a major determinant of poor outcome in esophageal adenocarcinoma. Epithelial–mesenchymal plasticity (EMP) enables dynamic cell state transitions that may...

Limited Discriminatory Capacity of Continuous Glucose Monitoring in Prediabetes and Increased Diabetes Risk: A Cross-Sectional Study

Background and Objectives: To determine whether continuous glucose monitoring (CGM)-derived metrics can differentiate between normoglycemia, increased diabetes risk (FINDRISC+) and prediabetes and to assess whether CGM-derived metrics provide additional discriminatory information...

The World Psychiatric Association (WPA) Guideline on Schizophrenia Spectrum Disorders Management for Low- and Middle-Income Countries

There is a pressing need to address the unique challenges of managing Schizophrenia Spectrum Disorders (SSD) in Low- and Middle-Income Countries (LMICs), where mental health resources are scarce and unevenly distributed. To develop this evidence-based guideline, we conducted a sy...