University of Oulu

Bariatric Surgery and Risk of Obesity-Related Cancer by Age and Sex

Importance Obesity is associated with elevated risks for multiple cancers. How bariatric surgery influences these risks across age and sex is insufficiently understood. Objective To evaluate the association between bariatric surgery and obesity-related cancer (breast, endometrial...

Health-related interpretation of human biomonitoring results – new and updated human biomonitoring guidance values from PARC and HBM4EU

During the first three years of the Partnership for the Assessment of Risks from Chemicals (PARC), we derived health-based human biomonitoring guidance values (HBM-GVs) for 11 substances to enable the direct health-related interpretation of human biomonitoring (HBM) results. HBM-...

Identification and operative vs. conservative vs. no treatment trial of breastfeeding-impeding lingual frenulum in newborn infants (LINNE): protocol for a randomized controlled trial (RCT) embedded in a prospective observational cohort study in Northern Finland

The lingual frenulum is an anatomical structure of the mouth. If it restricts the movement of the tongue, it is called a tongue-tie. Existing evidence has linked tongue-tie to breastfeeding difficulties. With growing emphasis on successful breastfeeding, the number of surgical in...

Hybrid Single-Walled Carbon Nanotube–Nanocellulose Networks as Current-Collector-Free Electrodes

Abstract Hybrid nanoarchitectures that combine structural functionality of nanocellulose (NC) with electrical conductivity of carbon nanotubes (CNTs) are of growing interest for electroanalytical electrode design. However, CNT:NC hybrid film electrodes reported to date typically...

Simultaneous obstacle avoidance and trajectory tracking for multi-robot systems via acceleration-level motion planning

Considerable attention has been directed toward collision-free trajectory tracking in multi-robot systems, for which CBFs have been widely adopted as a safety-critical tool. However, existing CBF methods are constrained by their dependence on maximum braking estimation. Moreover,...

Static-dynamic triggering mechanisms of rockburst in straight-walled arch roadways under different principal stress orientations and impact disturbances

This study investigates how principal-stress orientation affects impact disturbance triggered rockburst around straight-walled arch roadways. Coupled static-dynamic loading tests were conducted on specimens containing a straight-walled arch opening with orientation angles of 0°,...

Effects of Double-Primer Placement on Rock Fragmentation at Kevitsa Open Pit Mine

Abstract To address the lack of systematic production-scale evaluation of the effects of double-primer placement on blasting performance, this study presents a comparative analysis of two primer configurations. The double-primer placement consists of two primers positioned 2 m ab...

Career anchors of Finnish chief physicians’ career pathways to leadership

Purpose Physician leaders’ impact on healthcare leadership is well documented, yet factors influencing their progression into leadership roles remain less explored. This study investigates the career paths of Finnish chief physicians, focusing on the career anchors influencing th...

Dimerization of human PARP15 is required for NAD + binding and automodification

Abstract PARP proteins are enzymes catalyzing ADP-ribosylation, a well-conserved post-translational modification. In addition to the catalytic domain present in all PARPs, these proteins have a wide selection of other domains possessing different functions. Additional domains pre...

Defining data-driven business models in the context of sustainability

Purpose Data have been identified as a potential next source of value creation and competitive advantage for companies, giving rise to data-driven business models that rely on data as a key resource. Despite the central role of data in today's business, there is conceptual ambigu...

Exploring the conceptual foundations of social impact measurement in social enterprises: a systematic review of the literature

Purpose The purpose of this study is to examine the conceptual landscape of social impact measurement in social entrepreneurship research. Specifically, it aims to identify and clarify the major unresolved debates and ambiguities that hinder the development of standardized and ef...

Catching the spark: The role of electrodermal activity in understanding teacher enthusiasm and students' lesson enjoyment

Abstract Process‐oriented approaches are needed to understand the temporality and dynamics of teacher–student interactions in higher education classrooms. In this study, we follow a complexity science approach, based on non‐linear intra‐ and inter‐personal physiology methods, to...

Early interaction among public and private actors in public procurement: a boundary work perspective

Purpose This study aims to explore the boundary work strategies of buyers and suppliers during the early interaction phases of the public procurement process. It also examines how those strategies influence the transition from traditional arm’s-length interaction to relational in...

Two Modes of Reflection: How Temporal, Spatial, and Social Distances Affect Reflective Writing in Family Caregiving

Therapeutic writing offers significant benefits for well-being; however, for family caregivers, conventional fixed or user-initiated schedules often fail to align with their dynamic, high-stress reality. We conducted a three-week field study with 47 caregivers using a chatbot tha...

Ionospheric currents and auroral signatures during successive earthward bursty bulk flows and dipolarization: a 7 December 2023 case study

Earthward bursty bulk flows (BBFs) in the central plasma sheet are frequently accompanied by dipolarization fronts, and together they account for a large fraction of the energy and momentum transported from the magnetotail to the high-latitude ionosphere through field-aligned cur...

Age-based prognosis in oral tongue squamous cell carcinoma patients: A systematic review and meta-analysis

Abstract Background The prognostic significance of younger age in oral tongue squamous cell carcinoma (OTSCC) remains uncertain because age definitions, treatment strategies, outcome definitions, and adjustment methods vary substantially across studies. Objective To evaluate the...

Beyond Enabling Perspectives: How Organizational Conditions Shape Intertwined Forms of Professional Agency in Health and Social Care

Abstract The need to deepen our understanding of how organizational conditions shape the enactment of professional agency in the context of rapidly changing health and social care organizations is growing. Professional agency is understood in this study as a temporally embedded,...

Projecting global soil moisture droughts under climate change: characteristics, agricultural exposure, and adaptation insights

The intensification of global warming has increased the severity, frequency, and duration of extreme drought events, posing significant threats to agricultural stability. This study introduces a framework for assessing global agricultural drought impacts under climate change by i...

Exploring treatment burden and self-management experiences among adults receiving haemodialysis to inform person-centred digital care: a descriptive qualitative study

Person-centred care identifies the need to understand what matters to an individual, as opposed to what is the matter with them. Although digital technologies are increasingly used to support haemodialysis self-management, little is known about how the experiences of those receiv...

How does rewetting propagate through restored peatlands? An integrated surface–subsurface modelling analysis of water–table dynamics

Abstract Peatland restoration, through drainage suppression, is widely implemented to recover hydrological and ecological functions; however, the groundwater system responses governing rewetting efficiency remain insufficiently quantified across spatiotemporal scales. Here, a bor...