Institution
University of Otago
Recent research
- Health & MedicineOpen access
The global cardiovascular-kidney-liver-metabolic burden from 1990 to 2023
Background The cardiovascular-kidney-liver-metabolic (CKLM) framework represents the multi-organ interplay of systemic metabolic disorders that drive the global burden of cardiovascular diseases (CVD). Methods This study is a descriptive epidemiological analysis of the Global Bur...
- BiologyOpen access
Genomic indicators of gene function: a systematic assessment of the human genome
Abstract Proteins and non-coding RNAs are functional products of the genome that are central for crucial cellular processes. With recent technological advances, researchers can sequence genomes in the thousands and probe numerous genomic activities of many species and conditions....
- Society & EconomicsOpen access
Indigenous peoples experience a paradox in official statistics: deficit framing and surveillance through state data systems, alongside an urgent need for evidence to monitor inequities and advocate for policy change. In Aotearoa New Zealand, existing monitoring systems often fail...
- BiologyOpen access
Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS....
- Health & Medicine
OBJECTIVE: To describe and compare ethics and governance approval timelines for the Quality in Acute Stroke Care (QASC) Australasia Trial (2021-present) and Triage, Treatment, and Transfer of Patients with Stroke in Emergency Departments (T3) Trial (2012-2014), benchmarking again...
- AI & ComputingOpen access
Abstract Pathogen-pathogen interactions occur when infection with one pathogen influences one’s chance of infection or disease due to another. Increasingly, evidence suggests that interactions are a common feature of infectious disease epidemiology. However, due to both the nonli...
- Health & MedicineOpen access
Background: This study aimed to identify the factors associated with self-reported visual difficulty and uptake of spectacle/contact lens correction among women of reproductive age in Malawi. Methods: We conducted a cross-sectional secondary analysis of the 2024 Malawi Demographi...
- Health & MedicineOpen access
Patterns of Antibiotic Dispensing Among New Zealand Children: A Linkage Study
ABSTRACT Background Overuse of antibiotics contributes to antibiotic resistance, and may result in gut microbiome dysbiosis, potentially increasing the risk of chronic childhood conditions. Objectives To examine patterns of antibiotic dispensing in utero and during the first 5 ye...
- BiologyOpen access
<title>Abstract</title> Background: Minigene RT-PCR assays are widely used to assess variant impact on splicing, with increasing reports of massively parallel splicing assays (MPSAs) demonstrating potential to upscale diagnostic use of construct-based data. This study conducted a...
- Climate & EnvironmentOpen access
Context Globally, impacts of wildfire on fauna populations and our knowledge of these impacts, vary considerably. Information regarding wildfire effects on Aotearoa’s terrestrial fauna is meagre but interest in this topic is increasing alongside anthropogenic climate change. Aims...
- Climate & EnvironmentOpen access
Supercharged penguins—supplementary feeding reshapes tawaki/Fiordland penguin winter migration
Migration in a species is primarily a response to resource availability, shelter, thermoregulation, predator avoidance, or seasonal environmental change. Tawaki/Fiordland penguins ( Eudyptes pachyrhynchus ) have earned the nickname “marathon penguins” as they migrate 2,500 km fro...
- Health & Medicine
Background HIV testing is an integral component of prevention, reducing undiagnosed infection and promoting early treatment. Indigenous gay, bisexual and other men who have sex with men (GBM) are at increased risk of HIV and sexually transmitted infections (STIs), but may experie...
- Climate & EnvironmentOpen access
Abstract Zooplankton transfer substantial energy in aquatic food webs and are used as indicators of environmental change. Syntheses of zooplankton community dynamics globally require datasets that span a wide range of environmental gradients; however, these datasets are limited d...
- Health & MedicineOpen access
INTRODUCTION: Annual Diabetes Reviews (ADRs) are a key Ministry of Health initiative designed to ensure comprehensive annual assessment for people with diabetes in Aotearoa New Zealand. Although national guidance outlines core components, the consistency with which ADRs are deliv...
- Health & MedicineOpen access
INTRODUCTION: Pacific peoples experience significant health inequities. National health data often aggregate diverse Pacific communities into a single category, potentially masking important differences in social-context health needs between subgroups. AIM: This study aimed to de...
- Society & EconomicsOpen access
A transparent, document-based benchmark of the May-June 2026 New Zealand Phase 5 senior-physics consultation draft against AQA A-level Physics, Singapore-Cambridge H2 Physics, IB Physics HL, and Queensland Physics. The deposit includes the technical note, complete audit workbook,...
- Society & EconomicsOpen access
A transparent, document-based benchmark of the May-June 2026 New Zealand Phase 5 senior-physics consultation draft against AQA A-level Physics, Singapore-Cambridge H2 Physics, IB Physics HL, and Queensland Physics. The deposit includes the technical note, complete audit workbook,...
- Society & EconomicsOpen access
Abstract Introduction Education for Sustainable Healthcare (ESH) is a novel area of medical education and high-quality evidence to guide effective learning approaches is yet to be established. This study investigates the design of ESH in undergraduate medicine through the lenses...