University of Niigata Prefecture

Genetic Characterization of MAPT Exon 6 Variants in Indonesian Patients with Vascular Dementia: A Cross-Sectional Sequencing Study

Background The microtubule-associated protein tau (MAPT) gene plays a critical role in neuronal microtubule stabilization and has been widely implicated in neurodegenerative disorders, including vascular dementia. However, the molecular characterization of MAPT gene variants in p...

Clinical Phenotype of Apoe Ɛ4 Carriers In Patients With Vascular Dementia: A Cross-Sectional Study From Indonesia

Background Vascular dementia (VaD) is the second most common cause of dementia and exhibits substantial heterogeneity in cognitive, functional, and radiological manifestations. Despite the observed differences in clinical presentation, the factors responsible for this variability...