University of Nebraska at Omaha

The Inv(16) Oncogene CBFB::MYH11 is Required for the Survival of Leukemia Cells in the Blood and Spleen, but not the Bone Marrow

Inversion of chromosome 16 [inv(16)] generates the fusion gene CBFB::MYH11 (CM) and is one of the most common chromosomal rearrangements in Acute Myeloid Leukemia (AML). Expression of CM is required for leukemia initiation. Patients with inv(16) at diagnosis invariably have the r...

Hiring and screening practices in a sample of US law enforcement agencies

Purpose Hiring and screening processes shape who enters law enforcement, yet little is known about how agencies prioritize these requirements and publicly communicate them on their websites. As a result, it remains unclear how candidate suitability is defined in practice and how...