University of Miyazaki

Biphasic hypertriglyceridemia in pregnancy with apolipoprotein C-II deficiency

Apolipoprotein C-II (ApoC-II) deficiency is a rare genetic cause of familial chylomicronemia syndrome (FCS) that predisposes affected individuals to severe hypertriglyceridemia and acute pancreatitis. Evidence guiding management during pregnancy is limited. We report a woman with...

Leiomyosarcoma of the Renal Vein That Enlarged Laterally While Preserving the Structure of the Renal Vein Lumen

ABSTRACT Introduction Primary renal vein leiomyosarcoma is an extremely rare disease and the tumor often infiltrates the vessel wall. We report a case of primary renal vein leiomyosarcoma that enlarged while preserving the structure of the renal vein lumen. Case Presentation A 64...

Cardiovascular complications in adults with clinically diagnosed osteogenesis imperfecta: A cross-sectional study with echocardiography and magnetic resonance imaging

Background: Osteogenesis imperfecta (OI) is a congenital bone fragility disorder, in which 90% of patients have abnormalities in type 1 collagen. Cardiovascular complications, including valvular heart disease and vascular aneurysms, are reportedly comorbid with this disease. Meth...

Augmentation or Erosion? Regulating Cognitive Offloading in Generative AI-Supported STEM Learning

Generative artificial intelligence (GenAI) confronts educational psychology with sharply heterogeneous evidence: meta-analyses report positive average effects on learning alongside prediction intervals spanning harm to benefit, and experiments document gains in some configuration...

Quantitative total serum IgG4 reporting in human paragonimiasis: a scoping review

BACKGROUND: Paragonimiasis is a food-borne parasitic disease caused by lung flukes belonging to the genus Paragonimus. It can produce pulmonary, pleural, and other organ manifestations that overlap clinically, radiologically, and histopathologically with malignancy, tuberculosis,...

Principal specialization of monomial symmetric polynomials and group determinants of cyclic groups

Abstract In this paper, we study the principal specialization of monomial symmetric polynomials and investigate the special values of these polynomials at $$\begin{aligned} \zeta _{(n,k)} := ( 1, \zeta _n, \zeta _n^2, \dots , \zeta _n^{kn-1} ), \end{aligned}$$ ζ ( n , k ) : = ( 1...

Atmospheric Corrosion Behavior of Arc Thermal-Sprayed Zn–30mass%Al and Zn Coatings Under Different Airborne Salt Environments

Abstract Atmospheric exposure tests were conducted to evaluate the long-term corrosion behavior of Zn–30mass%Al thermal-sprayed coatings, Zn thermal-sprayed coatings, and hot-dip galvanized Zn coatings under different airborne salt environmental conditions, and an accelerated out...

Divergent proviral load trajectories and clonal dynamics of HTLV-1-infected cells during antirheumatic therapy in rheumatoid arthritis

The optimal management of human T-cell leukemia virus type 1 (HTLV-1) carriers requiring long-term immunomodulatory therapy remains unclear. Patients with rheumatoid arthritis (RA) living with HTLV-1 frequently receive antirheumatic therapy, raising concerns regarding the potenti...

Electric appliance usage measured by a sensor and frailty in Japan

Abstract Background The measurement of in-home activity for frailty is limited by poor adherence, recall bias in self-reported measurements, and difficulties with long-term tracking. Data on electrical appliance usage can estimate in-home activities and be measured every minute,...

Evaluation of clinical prognostic factors for radium-223 therapy in castration-resistant prostate cancer with bone metastases: the KYUCOG-1901 study

We evaluated clinical factors associated with symptomatic skeletal events (SSEs), radiographic progression-free survival (rPFS), and overall survival (OS) in patients with metastatic castration-resistant prostate cancer (mCRPC) and bone metastases treated with radium-223 (Ra-223)...

Human-inherited RORγT deficiency encompasses genetic heterogeneity, T cell deficiency, and clinical homogeneity

Abstract We previously reported inherited RORγT deficiency in seven patients from three ancestries (Chilean, Palestinian, Saudi Arabian) with mycobacterial disease and chronic mucocutaneous candidiasis (CMC). We report here five additional patients from different ancestries (Afgh...

Cryo-EM structures of the SurA–BAM complex reveal conformational changes in outer membrane protein assembly

The outer membrane (OM) of Gram-negative bacteria acts as a permeability barrier against toxic compounds. Its integrity is maintained by various outer membrane proteins (OMPs), which are inserted into the OM by the β-barrel assembly machinery (BAM) complex. The periplasmic chaper...

Naturally Occurring ZCCHC3 Variants Modulate Antiretroviral Activity in Cynomolgus Macaques

ABSTRACT Many mammalian cells restrict viral replication by utilizing various host restriction factors. We recently demonstrated that CCHC‐type zinc‐finger‐containing protein 3 (ZCCHC3) suppresses human immunodeficiency virus type 1 (HIV‐1) replication through multiple mechanisms...

Surface Pre-Coating of Fly Ash Ceramsite for Interfacial Microstructure Evolution and Mechanical Enhancement of Lightweight Concrete

The widespread application of fly ash ceramsite as a lightweight aggregate in high-performance concrete is restricted by its inherent defects, including high porosity, high water absorption rate and weak interfacial transition zone (ITZ). In this study, a surface pre-treatment st...

Ecological Drivers of Breeding Peak in Hamadryas Baboons (Papio hamadryas) Across Two Contrasting Habitats in Saudi Arabia

Reproduction could be the most important control point for the spread of hamadryas baboons (Papio hamadryas). Understanding the drivers of reproduction is necessary to determine which interventions may work best, in which locations, and at what time of year. We analyzed monthly v...

Prenatal Test Selection After First‐Trimester Ultrasound Abnormalities Within a Centralized Genetic Counseling System in Japan

This study evaluated the association between first-trimester ultrasound abnormalities and prenatal test selection within a centralized genetic counseling system in Japan. Advances in ultrasound screening and the increasing use of non-invasive prenatal testing (NIPT) have expanded...

Development and Validation of a Prediction Model for Alarm-Triggered Interventions in Pediatrics

BACKGROUND: Alarm fatigue in pediatric wards stems from frequent, nonactionable alarms that do not lead to clinical intervention. Predicting alarm-triggered clinical interventions is essential for optimizing monitoring strategies. OBJECTIVE: To identify factors associated with al...

Utilization of photovoltaic waste glass as fine aggregate in cement mortar: Effects of glass type, nitric acid treatment, and fly ash on alkali-silica reaction expansion and strength

This study investigates the feasibility of using photovoltaic (PV) waste glass as a sustainable fine aggregate replacement for natural sand in mortar by evaluating its alkali-silica reaction (ASR) reactivity and mechanical performance. Two types of waste glass, cover glass and su...

Working conditions, career barriers and perceived equity among neuro-oncology professionals: insights from the Japan society for neuro-oncology (JSNO) gender equality and diversity committee survey

<title>Abstract</title> Background Gender equity, work–life balance, and career development have become important concerns in the medical profession. However, empirical evidence on how neuro-oncology professionals experience working conditions, career barriers, and perceived ineq...

Urinary C5a as a Noninvasive Marker of Renal Activity, Histopathological Severity, and Outcomes in ANCA-Associated Vasculitis

Background: Complement activation plays a central role in the pathogenesis of ANCA-associated vasculitis (AAV). However, the clinical implications of urinary complement fragments remain unclear. We investigated whether urinary complement fragments reflect the severity of renal in...