University of Louisiana at Monroe

Inhibition of RNA-m6A Methylation in Breast Cancer Cells Carrying TP53 R273H Mutant Reactivates Natural Killer Cells for Anticancer Immunity

Oncogenic p53 mutant proteins not only promote cancer cell proliferation but also evade immune destruction for tumor progression. Besides hijacking immune checkpoints, p53 mutants in cancer cells may deactivate anticancer immune cells for evasion. Herein, we report that p53 R273H...