University of Khartoum

A conserved grain-associated immunosuppressive niche in Sudanese patients with mycetoma

Abstract Mycetoma is a neglected tropical disease caused by various bacterial and fungal pathogens that has a significant health impact across a broad geographically defined “mycetoma belt” spanning South America, Africa and Asia. Histologically, mycetoma is characterised by inva...

One in seven has severe pain: a point-prevalence study of hospitalised patients across Africa

ABSTRACT: Acute pain in hospitalised patients is common, yet African data are scarce. We conducted a prospective point-prevalence study of hospitalised adult patients across Africa to determine acute pain prevalence and severity and investigate associations of pain with critical...

Antibiotic susceptibility of genital tract isolates in pregnant women with premature pre-labour rupture of membranes (PPROM) in a low-resource setting

Premature pre - labour rupture of membranes (PPROM) is a significant obstetric complication that contributes to preterm births, maternal infections, and neonatal morbidity. The role of genital tract infections in the etiology of PPROM is well established, yet data on microbial is...

EUS-guided and US-guided percutaneous splenic biopsy: a systematic review and meta-analysis of separately pooled diagnostic and safety outcomes

Ultrasound (US)-guided percutaneous splenic biopsy has been widely used to evaluate focal or diffuse splenic lesions and has shown promising efficacy and safety. Endoscopic ultrasound (EUS)-guided biopsy has emerged as an alternative approach for tissue acquisition from splenic l...

The World Psychiatric Association (WPA) Guideline on Schizophrenia Spectrum Disorders Management for Low- and Middle-Income Countries

There is a pressing need to address the unique challenges of managing Schizophrenia Spectrum Disorders (SSD) in Low- and Middle-Income Countries (LMICs), where mental health resources are scarce and unevenly distributed. To develop this evidence-based guideline, we conducted a sy...

Ileal duplication cyst linked to type 3A ileal atresia: a rare case report and review of the literature

Background: Jejuno-ileal atresias represent a significant cause of neonatal intestinal obstruction, occurring in approximately 1 in 3000–5000 live births. Terminal ileal atresia, classified as type 3A according to the Louw and Barnard system, specifically involves a mesenteric de...

Ownership concentration and operational efficiency in emerging markets: the moderating role of market volatility

This study examines the relationship between ownership concentration, stock price volatility, and firm-level operational efficiency in an emerging market using a sample of 86 Saudi-listed firms from 2016 to 2023. To address potential endogeneity, the analysis employs instrumental...