University of Karachi

EMU detection of mysterious multiple component radio-continuum emission from nearby spiral Seyfert I type galaxy ‘Sand-timer’ (NGC 7213)

We present an Australian Square Kilometre Array Pathfinder (ASKAP) Evolutionary Map of the Universe (EMU) radio-continuum detection of the nearby spiral Seyfert I type galaxy NGC 7213 which we nickname ‘sand-timer’ due to its morphological appearance. We find an intriguing and pe...

Distribution of Rangelands and Freshwater Resources (Lentic & Lotic) in Khaplu, Ghanche, Gilgit‐Baltistan, Pakistan: A Baseline Study for Sustainable Management and Restoration of Natural Resources

ABSTRACT The natural resources of Gilgit‐Baltistan (GB), including rangelands and freshwater ecosystems, are facing unprecedented degradation due to climatic and anthropogenic pressures. However, baseline data for these critical resources in the understudied Khaplu Division remai...

Molecular detection and risk factors of carbapenemase -encoding gene among the Gram-negative uropathogens associated with catheter-associated urinary tract infection

Carbapenem-resistant Gram-negative bacteria frequently cause catheter-associated urinary tract infections (CA-UTIs). The objectives of this study included investigating prevalence, drug-resistance mechanisms, and risk factors associated with the infections caused by carbapenemase...

First-principles investigation of hydrogen storage in pristine AlN nanosheets with a biphenylene framework

Abstract One of the most important aspects of the energy transition towards sustainable development is the efficient storage of hydrogen, for which a diverse range of materials is being studied. Here, we investigated the structural and electronic characteristics of biphenylene al...

Between Aspiration and Infrastructure: The Opportunity-Reality Divergence in STEM Teacher Education in Karachi, Pakistan

A foundational assumption in applying Ajzen's Theory of Planned Behavior (TPB) to STEM teacher education is that prospective teachers' perceived behavioural control reflects the actual enabling conditions of their institutional environment. This study tests that assumption empiri...

Between Aspiration and Infrastructure: The Opportunity-Reality Divergence in STEM Teacher Education in Karachi, Pakistan

A foundational assumption in applying Ajzen's Theory of Planned Behavior (TPB) to STEM teacher education is that prospective teachers' perceived behavioural control reflects the actual enabling conditions of their institutional environment. This study tests that assumption empiri...

Real-world safety and effectiveness of empagliflozin (Diampa®) alone or in combination with metformin (Diampa-M®) in patients with type 2 diabetes mellitus in Pakistan: a multicenter observational study

Abstract Background Type 2 diabetes mellitus (T2DM) is a growing public health challenge in Pakistan, where poor glycemic control is common. Sodium–glucose co-transporter 2 (SGLT2) inhibitors, such as empagliflozin, have shown glycemic, cardiovascular, and renal benefits in contr...

First Report of Banana End Rot Caused by Corynespora torulosa in Pakistan

Banana (Musa acuminata Colla) is an important crop in Sindh, Pakistan, where Basrai (Dwarf Cavendish) is the dominant cultivar (Muhammad et al. 2020). In November 2023, banana end rot (BER) was observed on Basrai fruits in Naushehro Feroze District (26.7878°N, 68.2680°E). Only 3...

MSC-derived extracellular vesicles rescue ARPE-19 cells from H2O2-induced oxidative damage via antioxidant and anti-inflammatory mechanisms

Oxidative stress (OS) is a key factor in the pathogenesis of several eye conditions. Extracellular vesicles (EVs) isolated from human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) have emerged as a promising therapeutic agent due to their antioxidant and cytoprotective...

Deamidated Rice Protein as a Functional Fortificant in Wheat Flatbread

ABSTRACT Background and Objectives Wheat flatbread is a major dietary staple but has limited protein quality. This study evaluated native rice protein isolate (RPI) and rice protein isolate deamidated using a natural deep eutectic solvent (NADES) system (dRPI; 1%–5%, w/w) as clea...

Glucosamine functionalized multi-walled carbon nanotubes as potential antibacterial molecules

Antibiotic resistance represents a critical global health challenge driven by the widespread misuse of antimicrobials and the rapid evolution of multidrug-resistant pathogens. Conventional antibiotics are increasingly limited by poor stability, low bioavailability, toxicity, and...

Early versus delayed IV-to-oral antibiotic transition: clinical deterioration after oral switch and variation across regimen pathways

Objective This retrospective cohort study aims to assess associations of delayed Intravenous (IV)-to-Oral switch after 72-hours versus early switch within 72-hours with switch failure within 7-days and with adjusted post switch clinical outcomes in hospitalized adults.Methods Adu...

New Insights Into Electron Impact Mass Spectral Fragmentation of Restricted Aromatic Amines

ABSTRACT Many primary aromatic amines are powerful human carcinogens, which are occasionally found in adulterated food, textile and leather products and dyes. Gas chromatography (GC) coupled with electron impact (EI) mass spectrometry is a commonly used technique for their analys...

ASSET-LIGHT HYBRID SUKUK: LESSONS FROM INTERNATIONAL MARKETS FOR PAKISTAN'S RIBA-FREE ECONOMIC TRANSFORMATION

The role of Global Practices and Regulatory Readiness in Market Development and Riba Transformation in the context of Asset Light Hybrid Sukuk has been examined in this study and the moderating effect of Institutional Support has been analyzed in this study. A cross-sectional des...

ASSET-LIGHT HYBRID SUKUK: LESSONS FROM INTERNATIONAL MARKETS FOR PAKISTAN'S RIBA-FREE ECONOMIC TRANSFORMATION

The role of Global Practices and Regulatory Readiness in Market Development and Riba Transformation in the context of Asset Light Hybrid Sukuk has been examined in this study and the moderating effect of Institutional Support has been analyzed in this study. A cross-sectional des...

Moderate Biochar–Compost Mixture Is More Effective in Improving Biomass, Nutrient Fluxes, and Photosynthetic Outputs for Sustainable Land Restoration and Soil Fertility

ABSTRACT Soil nutrient depletion severely constrains crop productivity in degraded and saline environments. Strategies such as biochar–compost integration could be useful for sustainable agriculture and land restoration on a global scale. This study evaluated the effects of bioch...

Multivariate characterization of foliar morpho-anatomical traits supporting adaptive trends and taxonomic resolution in halophytic grasses

Leaf morphology and epidermal traits of 15 salt-tolerant grasses belonging to 10 genera from the Bahadur Khel Salt Range were examined using a microscopic technique for the first time. Eight qualitative characters (epidermal cell shape, anticlinal wall patterns, type of stomata a...

Residual Strength Prediction of Chemically Reactive Two‐Phase Nanofluid Flow in a Bingham–Papanastasiou Rheological Theory Using a Morlet‐Based Wavelet Neural Network Approach

ABSTRACT The behavior of nanofluid flow involving a zero‐mass flux condition has received considerable interest because of a realistic scenario. In reality, this condition confines the optimistic accumulation or disappearance of nanoparticles past a sheet, constructing a more phy...

Ternary Deep Eutectic Solvents in Analytical Chemistry: Design Principles, Sample-Preparation Strategies, and Emerging Sensing Applications

In this review, we emphasize on ternary deep eutectic solvents (TDESs) utilized in environmental and analytical chemistry for separation and sensing purposes in contrast to their binary counterparts, known as simple deep eutectic solvents (DESs). To ensure food security, high wat...