University of Guayaquil

Long-Term Aesthetic Performance of Freehand Direct Anterior Composite Resin Restorations: A Systematic Review and Meta-Analysis of Colour Alteration, Marginal Discolouration, and Surface-Quality Deterioration

Background: Freehand direct composite resin veneers offer a minimally invasive approach for managing aesthetic alterations in anterior teeth; however, their long-term colour alteration and surface performance remain uncertain. This systematic review evaluated colour alteration, m...

The Human Labial Superficial Musculoaponeurotic System (SMAS): Anatomy, Imaging, and Biomechanical and Sensory Implications—A Narrative Review

The superficial musculoaponeurotic system (SMAS) is a fundamental concept in facial anatomy and surgery, but its organization within the human lips remains incompletely defined. This narrative review critically reassesses the anatomical evidence for a labial SMAS and its regional...

Relación entre las prácticas de evaluación diagnóstica y la adaptación de estrategias didácticas en instituciones educativas fiscales

La evaluación diagnóstica constituye una práctica pedagógica necesaria para reconocer conocimientos previos, dificultades, ritmos de aprendizaje y necesidades del estudiantado en instituciones educativas fiscales. El objetivo del artículo fue analizar la relación entre las prácti...

Nutrient Solution and Harvest Age of Hydroponic Maize Fodder: Potential Influence on Chemical Composition, Rumen Digestion and Mitigation of Gas, CH4 and CO2 Emissions in Brahman Bulls

Forage scarcity, especially during dry periods, limits feed availability for livestock systems, affecting the productivity and sustainability of animal production. The aim of this investigation was to determine the effect of three harvest ages (8, 10 and 12 days) and five nutrien...

Antiproteinuric Response to Finerenone in Diabetic Kidney Disease: Responder and Non-Responder Subgroup Analysis of the FINDKDLATAM Study

Background/Objectives: Albuminuria is an early marker of kidney damage and an independent predictor of adverse outcomes, making its reduction a key therapeutic goal. Finerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, has demonstrated renal and cardiovascu...

Typed Indeterminacy Engineering: A Practitioner's Design Pattern for Carrying Uncertainty Types Through a Decision Pipeline

Decision systems that operate under uncertainty — LLM-as-judge evaluators, multi-criteria ranking procedures, evidence-fusion pipelines, AI alignment mechanisms, expert-consensus methods — routinely reduce heterogeneous epistemic failure modes to a single scalar of “confidence.”...

Can a card-based educational game enhance functional anatomy knowledge in first-year medical students? A mixed-methods study

Anatomy is a foundational yet cognitively demanding subject in undergraduate medical education. Although game-based learning has shown potential to enhance engagement and assessment performance, evidence remains limited for low-cost, single-session, card-based interventions desig...

Divergent Hypoxia-Inducible Factor 2-Alpha Signaling in Alcoholic Liver Disease and Metabolic Dysfunction-Associated Steatotic Liver Disease

Abstract Fatty liver disease, including both metabolic dysfunction-associated steatotic liver disease (MASLD) and alcoholic liver disease (ALD) types, is an increasing global health issue, with escalating rates of illness and death. A key player in the progression of these liver...

SIRR — Slope Intersection Reduced Reconstruction Method: Reconstruction of Clipped Seismic Peaks, Historical Formulation (1999–2000) and 2026 Single-Parameter Evolution

SIRR — Slope Intersection Reduced Reconstruction Method is a seismic signal reconstruction methodology developed to recover clipped seismic peaks in strong-motion accelerograms when the true ground acceleration exceeds the recording range of the instrument. The method originated...

SIRR — Slope Intersection Reduced Reconstruction Method: Reconstruction of Clipped Seismic Peaks, Historical Formulation (1999–2000) and 2026 Single-Parameter Evolution

SIRR — Slope Intersection Reduced Reconstruction Method is a seismic signal reconstruction methodology developed to recover clipped seismic peaks in strong-motion accelerograms when the true ground acceleration exceeds the recording range of the instrument. The method originated...

Síndrome Cardio Renal en Pacientes con Insuficiencia Cardiaca Prevención y Reducción de la mortalidad desde el ámbito de la medicina interna y cardiología

El síndrome cardiorrenal constituye una interacción bidireccional entre disfunción cardiaca y renal que incrementa hospitalización, progresión clínica y mortalidad en la insuficiencia cardiaca. El objetivo fue analizar los mecanismos fisiopatológicos, factores de riesgo, estrateg...

Síndrome Cardio Renal en Pacientes con Insuficiencia Cardiaca Prevención y Reducción de la mortalidad desde el ámbito de la medicina interna y cardiología

El síndrome cardiorrenal constituye una interacción bidireccional entre disfunción cardiaca y renal que incrementa hospitalización, progresión clínica y mortalidad en la insuficiencia cardiaca. El objetivo fue analizar los mecanismos fisiopatológicos, factores de riesgo, estrateg...

Design and Expert Validation of the MIGEAS Model: A Data Analytics-Driven Framework for Strategic Management and Functional Integration in Higher Education

Higher Education Institutions (HEIs) face increasing challenges in effectively integrating their core functions of Teaching, Research, and Community Engagement (TRCE) while responding to growing demands for quality, accountability, and data-informed governance. This study aimed t...

Clinical and Economic Burden of Complicated Pneumonia and Invasive Disease due to Streptococcus pneumoniae Serotype 19A in an Ecuadorian Pediatric Reference Hospital

Serotype 19A has emerged as an important cause of pneumococcal disease following the introduction of the 10-valent pneumococcal conjugate vaccine (PCV10). In this retrospective study of children hospitalized with culture-confirmed invasive pneumococcal disease at an Ecuadorian pe...