University of Göttingen

Beyond exact and asymptotic: optimization-based tuning of confidence intervals for proportions

Abstract Confidence interval estimation for binomial proportions remains challenging in finite samples due to the discreteness of the data, which induces oscillatory coverage behavior. Classical intervals are often conservative (e.g., Clopper–Pearson) or may exhibit undercoverage...

New insights into the evolution of Charlie Chaplin worms (Histriobdellidae, Eunicida, Annelida)

Abstract Histriobdellidae, the so-called Charlie Chaplin worms, is an enigmatic group of microscopic commensal annelids associated with crustaceans. They crawl by alternately attaching their adhesive anterior appendages and left and right huge lateral ‘feet’, and bear a complex j...

Manipulating prior causal beliefs affects the formation of apparent causal illusions

Non-contingent learning data can produce an apparent “illusory” or “false” perception of causality (“causal illusion”), especially if a potential cause and effect frequently co-occur — a phenomenon known as the “outcome-density bias.” In contrast to the prominent bias view, Bayes...

Electroreduction of Activated Esters Catalyzed bya Manganese Complex

Abstract Electrochemical hydrogenation (electrohydrogenation) using electrons and protons as H2 surrogates offers a sustainable alternative to conventional reduction methods. Herein, we report the manganese-catalyzed electroreduction of activated esters employing a derivative of...

Evaluating the classification performance and data requirements of Catch22 features on noisy and short synthetic time series

Abstract This study evaluates the performance, data requirements, and computational efficiency of the feature extraction tool Catch22 for time-series classification. Using synthetic sinusoidal signals and nonlinear signals generated with the FitzHugh-Nagumo (FHN) model, we system...

Modular Access to α ‐Tertiary Amines: Electrochemical Tandem Di‐Functionalization of Olefins With Ammonia Surrogates and Amino Acids

ABSTRACT Quaternary carbon centers, especially those bearing nitrogen, are highly valued in drug discovery, imparting three‐dimensionality, selectivity, and metabolic stability. Yet, accessing α ‐tertiary, primary amines ( α ‐TPAs) remains challenging due to steric congestion and...

Early reduction of forced-air warming temperature can reduce energy consumption during craniotomy: a prospective randomized trial

Despite their well-known efficacy, forced-air warming during operations has its drawbacks, mainly high energy consumption and risk of hyperthermia. We therefore investigated two warming strategies in a prospective randomized study with the aim of reducing the incidence of hyperth...

Quality is in the Eye of the Beholder: A Quality Model rethinking VET through the Eyes of Gen Z Learners - Individualization, Digitalization, and Meaningful Work

Abstract As Generation Z (Gen Z) enters vocational education, their distinct expectations and digital fluency present new challenges for dual vocational education and training (VET). While these issues are frequently discussed in public discourse, empirical evidence remains scarc...

Implementation barriers, facilitators, and fidelity of a mobile money-based savings tool for pregnant women in the Analamanga region of Madagascar: an ex-post process evaluation

Abstract Background Mobile payment services could improve access to obstetric care by easing saving, raising revenue, and pooling resources. Between 2019 and 2022, a mobile money-based savings tool for obstetric care was implemented in the Analamanga region of Madagascar followin...

Holocene hydroclimatic variability and multi-frequency analyses at Lake Sidi Ali (Morocco)

Abstract. The North African desert margin is considered one of the most sensitive areas to future climate changes, yet the periodicities, coupling mechanisms and external forcing of Holocene environmental variability remain poorly understood. To investigate millennial- to centenn...

Soil Microbiome Changes under Long-Term Rye and Maize Monocropping Systems, Crop Rotation and Bare Fallow under Different Fertilization Variants

Microbial communities are recognized as critical and essential factors in maintaining crop and soil health. However, our current understanding of soil microbial status, particularly in long-term monocropping systems, remains limited, especially concerning interactions and communi...

The relationship between language prediction and action prediction in toddlers and adults

Prediction plays a key role in both action processing and language comprehension, yet it remains unclear whether individual differences in action prediction are related to individual differences in language prediction. Using eye-tracking, we examined predictive looking behaviour...

Miocene Evolutionary History Shaped the Phylogeography of Willow Species (Salix L.) in the European Alps

In the European Alps, plant species have persisted through major geological and climatic changes, leaving distinct genetic signatures of divergence. While these patterns are often attributed to Pleistocene glacial refugia, they may also reflect older, pre-Quaternary events. In mo...

Mechanistic insights into the immunomodulatory and antibacterial activity of the Japanese Kampo Formula Hainosankyuto

Purpose This study aimed to quantify the in vitro antibacterial activity of the Japanese herbal formula Hainosankyuto (HNST) against Gram-positive and Gram-negative bacteria and to elucidate its immunomodulatory effects on human monocytes. Methods The antibacterial activity of HN...

Highly localized droplet clustering in shallow cumulus clouds

The size and spatial clustering of water droplets in warm clouds influence cloud evolution and radiation properties and thus are of fundamental importance for the Earth’s energy balance and water cycle. Some proposed mechanisms for droplet growth and precipitation initiation in w...

Polymer Substrates for Flexible Sensors: Advances and Contributions to Smart Agriculture

ABSTRACT The advancement of smart agriculture is becoming increasingly dependent on sensor technologies that enable the digitization and optimization of agricultural processes. Traditional sensors, however, are constrained by their inherent rigidity, poor conformability to irregu...

Beyond the Private Sphere: Women's Community Participation and Household Diet Quality in Rural China

ABSTRACT Improving diet quality remains a key challenge in post‐poverty rural China. This study examines how women's community participation, a form of public‐sphere agency, relates to household diet quality. We introduce a Food‐Weighted Dietary Diversity Index (FWDDI) that captu...

TFClassPredict: A Framework for Transcription Factor Binding Site Analysis based on DNA-Binding Domain Classes

TFCP_model.zip Contains the official fine-tuned DNABERT model for DNA-binding domain class prediction, as described in TFClassPredict. TFCP_precompiled.zip Contains precompiled genome-wide binding potential tracks in UCSC hg38 coordinates, provided as one genomic track per DNA-bi...