University of Foggia

External Load Demands in Italian Serie A: Do Winning Teams Run More Than Relegated Teams?

Soccer performance has gained increasing interest in recent years due to technological advancements. GPS technology is extensively used within professional contexts to quantify external load and support evidence-based training prescription for top-level players. The aim of this s...

Conservative Management of Pediatric Mandibular Condylar Fractures: A Systematic Review

ABSTRACT Mandibular condylar fractures are common mandibular injuries in children. Conservative treatment is generally favored because of the remodeling capacity of the growing condyle, although rehabilitation protocols and the criteria for operative treatment remain variable. Th...

The Italian Version of the Lesbian, Gay, Bisexual and Transgender Development of Clinical Skills Scale (LGBT-DOCSS): Validation Among Mental Health Professionals

INTRODUCTION: Sexual and gender minority (SGM) individuals experience substantial health inequalities, and clinical competence among healthcare providers is a key determinant of equitable care. The Lesbian, Gay, Bisexual and Transgender Development of Clinical Skills Scale (LGBT-...

Multimodal Neurorehabilitation Including Auditory EEG Neurofeedback: A Proof of Concept Tested After Resection of a Giant Olfactory Groove Meningioma

Background/Objectives: Patients undergoing resection of large olfactory groove meningiomas may present with persistent cognitive, behavioral, motor, and functional impairments. Evidence regarding EEG neurofeedback as part of postoperative neurorehabilitation remains preliminary....

Rheological Optimization of Reduced-Sugar Ice Cream Enriched with Inulin and Carob Flour

Sugar reduction is technologically challenging in ice cream because sugars contribute not only to sweetness but also to rheological properties. A D-optimal mixture design was applied to optimize the formulation of reduced-sugar ice cream using inulin and carob flour as functional...

The Multifaceted Role of the FLNC Gene in Hereditary Cardiomyopathies and Prognosis

Variants in the filamin C (FLNC) gene are increasingly recognized as causes of cardiac and skeletal muscle disease. Cardiomyopathy-associated FLNC variants span dilated cardiomyopathy (DCM), nondilated left ventricular cardiomyopathy (NDLVC), arrhythmogenic cardiomyopathy (ACM),...

Innovative positioning of respiratory allergen immunotherapy: a focus on precision medicine

Introduction Allergen immunotherapy (AIT) is the only treatment for IgE-mediated respiratory allergy that can modify disease progression. Historically, AIT has relied on empirical personalization, based on allergen selection and clinical judgment. However, AIT is now transitionin...

Interdental brushing behaviour in adults: Influence of periodontal status and socioeconomic factors

Abstract Aim To evaluate patterns of interdental brush (IB) use across different stages and grades of periodontitis and to examine associations with socioeconomic, demographic, and behavioural factors. Methods This cross-sectional study included 375 adults referred for secondary...

The Acceptance of Relationship Red Flags and Romantic Myths in Adolescents’ Judgments of Teen Dating Violence: A Cross-Sectional Vignette Study

Teen dating violence (TDV) is a prevalent phenomenon, yet the role of cognitive–attitudinal factors such as the acceptance of relational “red flags” and the endorsement of romantic myths remains insufficiently explored. This study investigates how these factors are associated wit...

Nutrition, Sedentary Behaviour and Physical Activity in Undergraduate Students: A Scoping Review with PRISMA-ScR Checklist

Background/Objectives: University students are particularly vulnerable to unhealthy lifestyle behaviours, including poor dietary habits, insufficient physical activity, and prolonged sedentary time. While these three behaviours have each been extensively studied individually, the...

Epiretinal Human Amniotic Membrane Overlay for Recurrent Retinal Detachment in Highly Myopic Eyes with Peripapillary Breaks over Chorioretinal Atrophy: Surgical Technique and Outcomes

Purpose: To evaluate the anatomical and functional outcomes of an epiretinal cryopreserved human amniotic membrane (hAM) overlay technique for the management of recurrent retinal detachment (RD) associated with peripapillary breaks in highly myopic eyes. Methods: Retrospective in...

Beyond Nasal Eosinophilia: Toward Integrated Cytological Patterns as Local Biomarkers

Dear Editor,I read with great interest the article by Neuschlova et al. [1], describing nasal eosinophilia as a non-invasive biomarker of type 2 inflammation and treatment response in childhood ast...

Chronic pain in Italy: exploring patient perspectives on care gaps and opportunities

Abstract Background : Chronic pain represents a significant public health burden, yet comprehensive data on patient perspectives in Italy remain limited. Despite Law 38/2010 guaranteeing access to pain therapy, gaps persist in understanding how patients experience care, navigate...

Pharmacological Profiling of Cannabinoid CB2 Receptor Ligands in Non-Stimulated BV-2 Microglia Cells

Microglia are key regulators of central nervous system homeostasis and neuroinflammation, and cannabinoid type 2 receptors (CB2Rs) have emerged as important modulators of microglial function. Although the pharmacology of CB2Rs has been extensively characterised in heterologous ex...

PIK3CA in Cancer: Structure, Biology, Alterations, and Actionability

PIK3CA, which encodes the p110α catalytic subunit of phosphoinositide 3-kinase (PI3K), is one of the most frequently altered oncogenes in human cancer and a major driver of tumor initiation, progression, metastasis, and therapeutic resistance. Over the past two decades, advances...

War, climate change, and mental health: a geopsychiatric perspective on an emerging global polycrisis

Abstract Background War, armed conflict, forced displacement, and climate change are increasingly interconnected determinants of mental health. A geopsychiatric perspective situates their effects within the interacting geographic, geopolitical, environmental, cultural, economic,...

Global Real‐World Outcomes of Olaparib in Metastatic Castration‐Resistant Prostate Cancer Patients With Homologous Recombination Repair Alterations

Evidence to guide the treatment for patients with metastatic castration-resistant prostate cancer (mCRPC) and Homologous Recombination Repair (HRR) gene alterations outside of clinical trials remains limited. This was an observational, cohort study, including mCRPC patients with...

Bad Blood: Navigating VTE Risk in Breast, Ovarian, and Endometrial Cancer

Cancer-associated thrombosis (CAT) is defined as venous or arterial thrombotic events occurring in patients with active malignancy or during anticancer treatment, most commonly presenting as venous thromboembolism and representing a leading cause of morbidity and mortality in onc...

Factors for Success and Failure of Allergen Immunotherapy ( AIT ) Trial Design in the Light of Evidence‐Based Medicine: Current Aspects 2026

Allergen immunotherapy (AIT) has been acknowledged as the only disease-modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized clinical trials (RCTs), the AIT study res...

Bladder multilithiasis across different clinical scenarios: Multimodality imaging findings, differential diagnosis, and complication assessment in 4 patients

Bladder calculi are an uncommon form of urolithiasis in developed countries and are usually associated with urinary stasis, bladder outlet obstruction, chronic catheterization, recurrent urinary tract infections, and neurogenic bladder dysfunction. Although their diagnosis is oft...