University of Florida Health Science Center

Thrombotic Thrombocytopenic Purpura Causing Multiple Large Vessel Occlusions: A Case Report

Background Thrombotic thrombocytopenic purpura (TTP) is a hematologic disorder characterized by a severe deficiency or absence of the disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 enzyme (ADAMTS13), which is a protease essential for cleaving von Wi...

Comparative evaluation of nephrotoxicity and antibacterial activity of free and liposomal gentamicin in rats: Biochemical, molecular and histopathological analysis

Gentamicin is a widely used aminoglycoside antibiotic; however, its clinical use is limited by dose-dependent nephrotoxicity. Liposomal drug delivery systems may reduce toxicity while preserving antibacterial efficacy. This study aimed to comparatively evaluate the nephrotoxic an...