University of Defence

From Strategic Bombing to Precision Strike: Continuity and Adaptation in Infrastructure Targeting

Infrastructure targeting has been a recurrent feature of modern warfare, but its history does not represent a linear transition from isolated targets to the discovery of interdependence. Interwar air-power theorists, particularly at the Air Corps Tactical School, already treated...

Immunopeptidomics reveals conserved and abundant Francisella tularensis proteins as immunogenic CD4 T cell antigens in mice

Human tularemia is caused by infection with the intracellular bacterium Francisella tularensis . The ability of the bacterium to cause a severe pneumonic form of the disease has led to concerns in the field of biodefense and efforts to develop a vaccine. F. tularensis LVS provide...

Quaternary ammonium compounds: outdated or relevant antiviral agents? A narrative review of QAC efficacy against enveloped and non-enveloped viruses

Quaternary ammonium compounds (QACs) are widely used disinfectants, favored for their broad antimicrobial action and safety profile. However, viral disinfection is complex and affected by multiple variables, including the virus’s envelope status, exposure time, temperature, and o...

Dinuclear Platinum(II)Complexes Targeting DNA andHuman Serum Albumin: Electrostatic Binding and Apoptosis-Driven AntiproliferativeActivity

Abstract Two novel dinuclear platinum(II) complexes, [{Pt(1,3-pnd)Cl}2(μ-4,4′-bipy)]Cl2 (Pt1) and [{Pt(1,3-pnd)Cl}2(μ-4,4′–SS–bipy)]Cl2 (Pt2), were synthesized and characterized by elemental analysis, UV–vis, and 1H/13C NMR spectroscopy. Spectroscopic and electrochemical studies...