University of Cyberjaya

Artificial intelligence and machine learning-enabled smart nanodrug delivery systems for tissue regeneration and precision therapeutic release

Rational nanoparticle design, stimuli-responsive release control, and release kinetics matching with changing tissue microenvironment are improving preclinical and clinical regenerative therapy results and clinical translation utilizing artificial intelligence and machine learnin...

Cyclotides from Clitoria ternatea: Genomic Organization, Biosynthesis, and Roles in Plant Defense

Clitoria ternatea, commonly known as butterfly pea, is a perennial legume widely recognized for its ornamental and medicinal value. Beyond its characteristic anthocyanin-rich blue flowers, the plant produces cyclotides, a type of ultra-stable, cyclic cystine-knot peptide, with ex...

Biotechnology-Enabled Diagnosis and Treatment of Drug-Resistant Tuberculosis in the Philippines

Abstract Drug-resistant tuberculosis (DR-TB) remains a major public health challenge in the Philippines, where a high disease burden is compounded by gaps in diagnosis, resistance testing, referral, treatment initiation, and continuity of care. This review examines how biotechnol...

Targeted deoxycholic acid-loaded nanoliposomes enhance cell-associated uptake and modulate polarization-associated markers in THP-1-derived M2-like macrophages

Abstract Tumor-associated macrophages (TAMs) frequently exhibit M2-like properties that support tumor progression. Deoxycholic acid (DCA), a secondary bile acid with amphiphilic membrane activity and context-dependent immunomodulatory effects, may influence macrophage phenotype....

Bavachin Attenuates Cognitive Impairment in Scopolamine‐Induced Amnesia: Behavioral, Biochemical and Molecular Insights

ABSTRACT Cholinergic dysfunction is a key feature of cognitive impairment, and currently available acetylcholinesterase (AChE) inhibitors provide limited symptomatic benefit and are often associated with adverse effects. This study evaluated the cognitive‐protective effects of ba...

Oncolytic virotherapy in cancer: cellular mechanisms, engineering strategies, and clinical translation

Abstract Oncolytic viruses (OVs) combine tumour-selective infection and replication with direct tumour-cell destruction and the capacity to induce antitumour immune responses. This review critically synthesises the cellular mechanisms, engineering strategies, preclinical developm...

Stakeholder-informed pre-implementation refinement of a pharmacy-led pre-exposure prophylaxis (PrEP) service delivery model in Malaysia

Introduction In 2024, only 3,451 individuals accessed free oral HIV pre-exposure prophylaxis (PrEP) at government clinics in Malaysia, despite an estimated 354,000 key population members who could benefit from PrEP. To inform pre-implementation refinement of a pharmacy-led PrEP s...

INVESTIGATING THE RELATIONSHIP BETWEEN SCHOOL LEADERSHIP STYLE, MOTIVATION AND TEACHER JOB SATISFACTION: THE CASE OF ASOSSA ZONE SECONDARY SCHOOLS OF BENISHANGUL GUMUZ REGIONAL STATE

ABSTRACT The role of school leadership in shaping the educational environment is critical, particularly in developing regions. This research investigates the nexus between transformational leadership, teacher motivation and job satisfaction in Asossa Zone public high schools, Eth...

How Is AI Transforming the Task Characteristics and the Experience of Vulnerable and Minority Employees in the Hospitality Sector?

ABSTRACT Drawing on Task–Technology Fit (TTF) theory, this study examines how different levels of Artificial Intelligence (AI) reshape service tasks and employee experiences among vulnerable and minority employees in the hospitality industry. A three‐phase mixed‐method design was...