University of Colombo

Characterizing the impact of incorporating spatially aggregated human mobility data into infectious disease models

Abstract Models of infectious disease dynamics should align the spatial scale of mobility data to the scale of travel relevant to infer disease introduction events and subsequent local transmission. Despite this, the biases of spatially aggregating mobility data, which are more c...

Translational evidence for the antihypertensive potential of Passiflora edulis: a systematic review of preclinical and clinical studies

Abstract Introduction Passiflora edulis (PE) (passion fruit) is traditionally valued for its cardiovascular and calming properties, but its antihypertensive and blood pressure (BP)-lowering potential has not been systematically evaluated. Emerging evidence from preclinical and cl...

Psychological distress among acute coronary syndrome patients – a descriptive cross-sectional study in patients managed at an interventional cardiology unit in Sri Lanka

<title>Abstract</title> <bold>Background</bold> Mental health issues are a globally prevalent problem. Psychological distress is an emotional and behavioural response to a stressor and can even lead to mental health disease. It is also associated with cardiovascular disease inclu...

Perception and Attitude Towards Home-Based Dialysis Treatments Among Patients with Chronic Kidney Disease: A Sri Lankan Single-Centre Cross-Sectional Observational Study

Background Despite the increasing prevalence of chronic kidney disease (CKD) and end-stage kidney disease (ESKD) in Sri Lanka, the uptake of peritoneal dialysis (PD) remains low. Materials and Methods This was a single-center cross-sectional study among patients with stage 4-5 CK...

Infections and Their Associations Among Patients with Systemic Lupus Erythematosus: A Retrospective Cohort Study in Sri Lanka

Background: Infections cause significant morbidity and mortality in systemic lupus erythematosus (SLE). This study describes infection prevalence, patterns, and their association with disease severity and flares in a single-centre Sri Lankan SLE cohort. Methods: This retrospectiv...

A salutogenic mobile health application for adolescent oral health: development and feasibility study

The health model of salutogenesis, has the potential to develop and implement digital health interventions, many of which are focused on self-care. Sense of coherence and generalized resistance resources are two key concepts of the health model of salutogenesis. The aim of this s...