University of California, Santa Cruz

A modular in-incubator microscope for longitudinal live-cell microscopy

Longitudinal live-cell imaging is valuable for characterizing morphological and phenotypic changes in biological systems. However, conventional approaches rely on manual microscope operation, which is labor-intensive, limits imaging frequency, and disrupts cellular environments....

Tracing the Cosmic Origins: Machine Learning Reconstruction of the Primordial Density Field from EoR Observations

Abstract Reconstructing the initial conditions of the Universe from late-time tracers would unlock cosmological information buried by non-linear structure formation and astrophysics. We reconstruct the initial density field corresponding to z = 300, with its linear amplitude extr...

Toward Sustainable Aquaculture: Microalgae Fully Replace Fishmeal and Fish Oil in Rainbow Trout Diets While Maintaining Growth, Nutritional Quality, and Cost Viability

As global demand for affordable, high-quality protein continues to rise, commercial aquaculture has emerged as a critical solution. The industry’s reliance on ocean-derived fishmeal (FM) and fish oil (FO) for aquafeed poses sustainability concerns. Marine microalgae offer a promi...

Increases in foraging performance of humpback whales in multi-predator feeding aggregations with California sea lions

Abstract Marine predators frequently form ephemeral multi-predator feeding aggregations around dense prey patches, yet the mechanisms and outcomes of these dynamic events remain poorly resolved. We quantified how California sea lion (Zalophus californianus) presence influenced hu...

A systematic fluorescently tagged protein toolkit for dissecting apical extracellular matrix patterning in C. elegans

Barrier epithelia are shielded from the external environment by their apical extracellular matrices (aECMs). The molecular complexity of aECMs has challenged understanding of their organization in vivo. To define the molecular architecture of a model aECM we generated a toolkit o...

Machine Learning on Heterogeneous, Edge, and Quantum Hardware for Particle Physics

The next generation of particle physics experiments will face an era of challenges in data acquisition, due to unprecedented data rates and volumes along with extreme environments and operational constraints. Harnessing these data for scientific discovery demands real-time infere...

Active inference with reusable state-dependent value profiles

Optimal behavior in volatile environments requires agents to deploy different value-control regimes across hidden latent structures. However, representing independent preferences, biases, and action confidence for every situation is computationally and statistically intractable....

Message in a bottleneck: Nested founder effects from French Polynesia to Rapa Nui and Hawaiʻi

Founder effects can lead to strong, population-specific allele frequency differentiation, including autosomal recessive conditions. Their characterization in European-descent groups, such as the Finnish and Amish, has resulted in actionable genetic tests for each. We show that Po...

A fast radio burst at redshift 2, three billion years after the Big Bang

Fast radio bursts (FRBs) are millisecond-duration radio transients from extragalactic sources. Their frequency and polarization properties are affected by plasma and magnetic fields along the line of sight to Earth. We report radio observations of FRB 20240304B and near-infrared...

Passive sampling for grazer cues incorporates top-down effects in harmful algal bloom monitoring and toxin prediction

Domoic acid (DA) produced by toxigenic species of the diatom genus Pseudo-nitzschia during harmful algal blooms (HABs) bioaccumulates in filter feeders, bait fish, and commercial seafood products, posing a threat to marine organisms and public health. Copepodamides, a group of po...

Mixtures of Neural Network Experts With Application to Phytoplankton Flow Cytometry Data

ABSTRACT Flow cytometry is a valuable technique that measures the optical properties of particles at a single‐cell resolution. When deployed in the ocean, flow cytometry allows oceanographers to study different types of photosynthetic microbes called phytoplankton. It is of great...

Robust recovery: resprouting and water stress response of a mixed evergreen forest following wildfire and salvage logging

Abstract Key Message Post-wildfire salvage logging did not significantly impact the physiological recovery of resprouts in four evergreen hardwood tree species, suggesting salvage logging can be an effective post-fire management practice in mixed evergreen forests. Abstract Wildf...

The downward legacy of a phytoplankton bloom in the oligotrophic North Pacific Subtropical Gyre

Abstract Ocean particles are a heterogeneous collection, including living and dead cells, feces, mucus‐rich aggregates, and mineral shells and frustules. In the well‐lit upper ocean, phototrophic processes fuel production of particulate matter; however, only a relatively small pe...

Uniform automated analysis of Sdiff splitting due to lowermost mantle anisotropy: Caveats and curated global dataset

Summary Seismic anisotropy, the dependence of seismic wave speeds on the direction of propagation and/or polarization, places crucial constraints on deformation and convective flow in the lowermost mantle (the D″ layer). Shear waves that diffract along the core-mantle boundary (C...

Extension of the Pnictinous Acid Series: Rational Synthesis of a Stibinous Acid and Exploration of Its Reactivity

Abstract The oxyacids of the heavy group 15 elements remain underexplored despite the important role that main-group oxyacids play in academic and industrial chemistry. Higher-valent oxyacids of heavier main-group elements readily polymerize because of their ability to expand the...

Multilingual Hispanic Speech in California (MuHSiC): A Large-Scale Open-Access Spanish–English Bilingual Corpus

Aims and Objectives / Purpose / Research Questions: This article introduces the Multilingual Hispanic Speech in California (MuHSiC) corpus. It addresses two primary questions: (a) how can a large-scale, open-access corpus be designed to capture the linguistic diversity of Spanish...

Small area estimation in low- and middle-income countries with the sae4health R shiny application

Abstract Accurate subnational estimation of health indicators is critical for public health planning, particularly in low- and middle-income countries, where data and analytic tools are often limited. sae4health is an open-access Shiny application ( https://rsc.stat.washington.ed...

Timelike Liouville theory and AdS3 gravity at finite cutoff

A bstract We propose that AdS 3 gravity with conformal boundary conditions is described by coupling the holographic CFT 2 to timelike Liouville theory and deforming by an exactly marginal operator. In this description, the Liouville field controls the finite-cutoff radial wall in...

Distance Estimation using Globular Clusters and Ultra-Compact Dwarfs

Abstract The tight scaling relation between absolute magnitude and internal velocity dispersion (σ) for globular clusters (GCs), referred to as the GC velocity dispersion (GCVD) relation, has shown great potential as a distance estimator. However, at the high-luminosity end of th...

Stellar masses of optically dark galaxies: uncertainty introduced by the attenuation law and star-formation histories

Abstract Recent studies using JWST have suggested that some high-redshift galaxies may be ultra-massive, thereby challenging standard models of early galaxy formation. We analyse the stellar masses using different modelling assumptions and in conjunction with new data of three ga...