University of Balochistan

Design, synthesis, and biological evaluation of pyrimidine linked fused thiazole–isoxazole conjugates as dual cholinesterase inhibitors for Alzheimer’s disease

Abstract Alzheimer’s disease (AD) affects over 55 million individuals worldwide, yet approved pharmacotherapies remain limited to symptomatic relief. Dual inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) offers a validated approach to restoring choliner...

Exploring the influence of firm digital transformation on sustainable competitive advantage through organizational agility with moderation of knowledge sharing

The paper examines the construct of digital transformation (DT) and its role in the sustainable competitive advantage (SCA) in project-based firms in Pakistan, namely in the construction, information technology, manufacturing, and service industries. The paper investigates the ef...