University of Algarve

Well-being in digital-free tourism: A mixed-methods rhythmanalysis

Tourism research has largely treated well-being as a motivation or outcome, neglecting how it unfolds in-situ and relying on self-report data. Through a mixed-methods rhythmanalysis, this study examines how well-being emerges and evolves in digital-free tourism. Following 23 part...

Clarifying Stratigraphic Terminology in Paleolithic Archaeology Using Natural Language Processing

Abstract Archaeological context is a foundational concept, yet its definition remains ambiguous and inconsistent. Traditionally, lithostratigraphic frameworks rooted in geology have long dominated, but recent computational and spatial approaches increasingly redefine stratigraphi...

Advances in Mental Health and Well-Being in Children (2nd Edition)

The promotion of mental health and well-being in children and adolescents is currently one of the key priorities in research, clinical practice, and public policy [...]

Metabolic dysfunction in chronic critical illness: mechanisms, clinical consequences and therapeutic perspectives

Advances in intensive care have improved survival from acute critical illness, leading to a growing population of patients with chronic critical illness (CCI), many of whom require prolonged organ support. This condition is associated with persistent catabolism, inflammation, and...

Polysaccharide Reengineering: Strategic Modifications and Biofunctional Outcomes of Natural Polysaccharides

Natural polysaccharides have attracted considerable interest in pharmaceutical and biomedical applications. However, native polysaccharides often possess limitations, like poor solubility, inadequate mechanical strength, limited stability, and insufficient control over their func...

Aterian Lithic Technology and Functional Studies in North Africa: A Review of Current Evidence and Perspectives

Abstract In North Africa, the Middle Stone Age (MSA) has been associated with the emergence and evolution of Homo sapiens and is considered a pivotal period in the development of behavioral complexity. Recent archaeological discoveries have yielded a range of technological innova...

Southern Portugal hydroclimate of the last millennium from near‐annually resolved speleothem records

ABSTRACT Hydroclimate in Portugal is influenced by the North Atlantic subtropical high‐pressure system (the Azores High) and by internal climate modes, most prominently the North Atlantic Oscillation, which may shift in position and/or intensity due to anthropogenic climate chang...

Environmental DNA for detecting marine fish species: testing the volume of sampled water, markers and primers in a public oceanarium

To maximize the efficiency of marine fish detection using environmental DNA (eDNA) metabarcoding, methodological factors such as PCR amplification bias and sampled water volume must be carefully considered. In this study, we evaluated the influence of different genetic markers (C...

β‐myrcene: A nature‐identical compound for sustainable aquaculture

Abstract Sustainability is essential for the continued development of aquaculture. A key aspect of sustainable aquaculture involves using natural and organic compounds as alternatives to chemical counterparts. Herbal‐derived compounds have gained significant attention because of...

Faunal Evidence and the Duration of Occupation: A Statistical Approach to Neanderthal Archaeological Sites

Abstract The duration of Neanderthal occupations of caves and rock shelters is one of the most debated issues in prehistoric archaeology. Several disciplines, including lithic analysis, micromorphology, zooarchaeology, taphonomy, and spatial archaeology, have proposed criteria to...

Flexible Late Mousterian lithic technological organisation at Riparo l’Oscurusciuto (Italy): A typo-technological and 3D-based approach

Abstract The portion of the Riparo l’Oscurusciuto (Italy) stratigraphic sequence so far excavated provides an outstanding record of the local population history between ca. 55 − 42 kya BP: a key period for understanding the end of the Middle Palaeolithic and the onset of the Uppe...

Analysis of postural control through nonlinear methods in older adults: a randomized controlled trial

Background Human balance and body orientation are regulated by the postural control system, which plays a critical role in stability, particularly with advancing age. Objective This study examined the effects of a sensorimotor training program on postural control in older adults...

International Protocol for the Study of Amorphous Charred Objects in Archaeology (IPSACO 1.0)

Abstract Archaeobotanists around the world increasingly recognise that, alongside commonly studied materials such as seeds, fruits, wood charcoal, and chaff, archaeobotanical samples also contain fragments of carbonised organic (and sometimes inorganic) matter that vary in shape...

The gut microbiome of old people in a Portuguese population is associated with Rural-Urban residence: impact on the metabolic profile and functionality

Abstract Background The gut microbiome mirrors unique characteristics of different locations and lifestyle, and old adults experience alterations in the gut microbiome potentially associated with the living setting. This study aimed to characterize the intestinal microbiome and e...

Archaeozoology and Biomolecular Analysis in Archaic Phoenician Gadir—The Site of Sagasta–Tinte (9th–8th Centuries BC)

Faunal remains constitute one of the main sources of evidence for reconstructing foodways and economic practices in Phoenician societies. Archaeological research conducted over recent decades in the Iberian Peninsula has highlighted their importance for understanding food product...

Prognostic Role of Adverse Events in a Worldwide Population of Patients with Biliary Tract Cancer Treated with Chemo-Immunotherapy

Background: Biliary tract cancers (BTCs) are aggressive malignancies with limited treatment options. The addition of durvalumab or pembrolizumab to cisplatin–gemcitabine improves overall survival (OS), but validated biomarkers of benefit remain limited. Immune-mediated adverse ev...

Multifunctional CMC–Nanographene Oxide Hydrogels Couple Fluorophore-Free Cancer Cell Imaging with Antioxidant and Antimicrobial Activity

Background: The development of sustainable biomaterials that combine imaging capability with complementary biological functions without relying on incorporated drugs or exogenous fluorophores represents an attractive strategy for multifunctional biomedical platforms. Methods: Her...

Dual effect of α-synuclein disease variants on condensate formation

Abstract α-synuclein is a pre-synaptic protein implicated in synucleinopathies including Parkinson’s disease, Parkinson’s disease dementia, and dementia with Lewy bodies, where it accumulates in intracellular aggregates termed Lewy bodies and Lewy neurites. Recent studies have re...

Geomorphological dynamics at the coast: A sedimentary stratigraphy for Atlit-Yam, the earliest coastal village at the Eastern Mediterranean and its submerged landscape

During the early Holocene, rapid sea level rise led to the inundation of worldwide coastal areas, with the surrounding shallow landscapes being the most affected. The Carmel coast, located in the East Mediterranean, preserves a rich record of such a submerged landscape dotted by...

Tracking Variability in Atmospheric, Oceanic, and Riverine Inputs to the Iberian Margin Over the Last 250 kyr

Abstract The Iberian Margin provides an exceptional archive of climate variability due to its high sedimentation rates. However, uncertainties persist regarding the provenance of terrigenous detrital sediments on the Iberian Margin, and the climate‐driven changes in their source...