University of Alberta Hospital

Comparing Cardiac Genetic Testing Pathways: Impacts on Access, Informed Choice, and Decisional Satisfaction

Abstract Background Mainstreaming genetic testing has emerged as a strategy to improve access and reduce wait times for patients who may benefit from genetic testing. Ensuring patients fully grasp the implications of testing when formal genetic counselling is not provided, remain...

Maternal and fetal cardiovascular response to moderate-to-vigorous intensity exercise in singleton and twin pregnancies

Objective Current guidelines suggest limiting physical activity in pregnant individuals carrying twins but this recommendation is not based on empirical evidence. We assessed maternal and fetal cardiovascular response to submaximal exercise testing in singleton versus twin pregna...

Diagnostic yield of repeat CT pulmonary angiography after a negative examination in the emergency department

PURPOSE: Although repeat CT pulmonary angiography (CTPA) after a negative index examination in the emergency department (ED) is common, its diagnostic utility remains uncertain. This study aimed to determine the incidence and diagnostic yield of repeat CTPA after a negative index...

The DLX/Notch axis is necessary for spatiotemporal regulation of neural cell fate

Neuronal-glial cell fate switch during forebrain development is highly regulated. DLX transcription factors are necessary for promoting GABAergic interneuron differentiation and migration but the mechanisms for concomitant repression of glial fate in neural progenitors remain elu...

Performance of the 2025 ASAS-Spartan Revised Classification Criteria for Axial Spondyloarthritis in a Canadian Multicenter Inception Cohort with Psoriasis, Uveitis, or Colitis Presenting with Undiagnosed Back Pain

Objectives To test the performance of the 2025 ASAS-SPARTAN Revised Classification Criteria for Axial Spondyloarthritis (axSpA)[1] in a multicenter inception cohort of patients with undiagnosed chronic back pain attending dermatology, ophthalmology, and gastroenterology clinics w...