University Malaya Medical Centre

Experimental and numerical evaluation of heat transfer and pressure drop using acid-functionalized titanium dioxide nanofluids in separation flow passage

Nanofluids have progressively gained popularity as thermodynamic fluids due to their intriguing qualities in terms of thermal conductivity. Though the nanofluids have gained greater attention in heat-transfer applications, their suspension stability is still not resolved, especia...

Characterisation of monocyte migration potential in response to stimuli from human arthroplasty revision xenograft transplanted in a NOD-SCID mouse model

Monocyte migration into periprosthetic tissue in response to wear debris-induced inflammation factors (WDIF) has been identified as one of the primary contributors to the progression of osteolysis in aseptic loosening (AL) of arthroplasty implants. However, the dynamics of monocy...

Ferroptosis and Iron Dyshomeostasis as Drivers of Wound Chronicity in Diabetic Foot Ulcers: Pathophysiological Mechanisms and Targeted Therapeutic Strategies

Background diabetic foot ulcers (DFUs) carry 5-year mortality rates of 50%–70% and recurrence rates of 65% at three to five years. Standard-of-care protocols fail to resolve wound chronicity in a substantial proportion of patients, reflecting incomplete understanding of the cellu...