University Hospital Olomouc

Changes in self-reported smoking among university hospital employees over two decades: a repeated cross-sectional study

Abstract Background Smoking among hospital employees remains an important public and occupational health concern. Healthcare professionals are particularly relevant because of their role in smoking prevention and cessation. This study compared self-reported smoking prevalence amo...

Preferential antiproliferative activity of an oleandrigenin-derived androstane toward prostate cancer cells

Abstract Cardiac glycosides, traditionally used for heart failure, are increasingly recognized for their anticancer potential. This study evaluated the in vitro antitumor activity of ten cardiac glycoside derivatives on androgen-insensitive (DU-145) and androgen-sensitive (LNCaP)...

Non-invasive detection of obstructive sleep apnea from speech in a limited clinical dataset

Abstract This study investigates non-invasive detection of obstructive sleep apnea (OSA) from daytime speech in a limited polysomnography-labeled clinical cohort. The objective was to evaluate whether speaker-verification-inspired representations can support robust speech-based O...

Clinicopathological Characteristics and Outcomes of Primary Parotid Gland Carcinomas in the Czech Republic: a Multicenter Retrospective Cohort Study of 453 Surgically Treated Patients

Parotid gland carcinomas are rare malignancies with marked histological and biological heterogeneity. Most published evidence is derived from single-center or selected institutional series, whereas comprehensive nationwide epidemiological data remain limited. The aim of this stud...