University Hospital of Larissa

Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026

Abstract Background Gastric cancer (GC) remains a major global health burden, and early detection is essential for improving patient outcomes. Although GC screening has been widely implemented in East Asian countries with a high disease burden, the optimal screening strategy for...

Prognostic Utility and Clinical Impact of Soluble Urokinase Plasminogen Activator Receptor in Adult Emergency and Acute-Care Patients: A Systematic Review and Narrative Synthesis

Soluble urokinase plasminogen activator receptor (suPAR) reflects systemic immune activation and biological vulnerability and has been proposed as a cross-diagnostic prognostic biomarker in emergency care. We systematically reviewed full-text English-language reports published fr...

Diagnostic Performance of the Lymphocyte Transformation Test and Patch Testing in Delayed Hypersensitivity Drug Reactions

Background: Cutaneous adverse drug reactions (CADRs) occur in 2–5% of inpatients, primarily due to delayed (T-cell-mediated) reactions, such as maculopapular exanthemas (MPEs). The lymphocyte transformation test (LTT) detects drug-specific T-cell responses with varied sensitivity...

Advancing cancer care for adolescents and young adults: the role of the European Network of Expertise

Adolescents and young adults (AYAs, aged 15-39 years at cancer diagnosis) are recognized as a distinct patient group with specific clinical and psychosocial needs requiring tailored care. This article presents the Network of Expertise (NoE) on AYAs with cancer developed through t...

Biologic Therapy in Pregnant Women with Plaque Psoriasis: A Narrative Review of Maternal and Fetal Safety Considerations

Background: Psoriasis in pregnancy is a highly prevalent inflammatory condition worldwide, with patients asking how the disease itself, as well as the medications that they take, would affect the general health of the fetus and the course of pregnancy. Objectives: This narrative...

Smoking-associated inflammation: A dual 18F-FDG PET/CT analysis of tonsillar and aortic inflammation using liver-normalized SUVmax.

OBJECTIVE: F-FDG) positron emission tomography/computed tomography (PET/CT) with liver-normalized maximum standardized uptake value (SUVmax) to assess metabolic inflammation in Waldeyer's ring and the thoracic aorta across smoking groups. SUBJECTS AND METHODS: F-FDG PET/CT scans...

Cause of death in a contemporary cohort of patients with pulmonary arterial hypertension

Abstract Background In pulmonary arterial hypertension (PAH), contemporary risk tools primarily estimate all-cause mortality, offering limited insight into what patients die from. Aims We aimed to characterize causes of death across baseline risk strata and to examine baseline fa...

Metaverse Implications: A Taxonomy

The metaverse is emerging as a transformative virtual environment that promises to reshape people's lives, introducing broad technological, social, economic, and cultural changes. Despite growing academic interest, existing literature remains dispersed, addressing isolated techno...

Cancer-associated myositis: a single-centre 20-year experience

BACKGROUND: Malignancy identified around the onset of idiopathic inflammatory myopathy (IIM) is referred to as cancer-associated myositis (CAM), but population-specific data remain relatively limited. AIM: To describe the prevalence, clinical features, and risk factors for CAM ov...