University Clinic of Traumatology

Fluid dynamics-informed CCTA-derived geometric parameters in right coronary artery anomalies predict abnormal invasive Adenosine-FFR and Dobutamine-FFR.

Background Traditional anatomical assessment of stenosis in right anomalous aortic origin of coronary arteries (R-AAOCA) may not capture the complex, eccentrically shaped lumen and its perimeter-dependent resistance, and may therefore underestimate flow limitation. R-AAOCA involv...

Neural signatures of major depression across the episodic memory circuitry.

In major depressive disorder (MDD), episodic memory is compromised and linked to hippocampal dysfunction, yet the underlying neural circuitry remains poorly understood. We examined the circuits supporting episodic memory and assessed its MDD-associated anatomical connectivity fin...

Association between aldehyde dehydrogenase 4 family member A1 plasma concentrations and atherosclerotic disease in patients with ischemic stroke: Results from the prospective multicenter BIOSIGNAL study.

Background The role of Aldehyde Dehydrogenase 4 Family Member A1 (ALDH4A1) in atherosclerotic disease is unclear. Experimental data suggests a possible involvement in atherogenesis. We investigated the association between circulating ALDH4A1 and atherosclerotic disease outcome me...

Functional Outcomes and Safety of Endovascular Thrombectomy in Pediatric Acute Ischemic Stroke With Cardiac Abnormalities.

Background And Objectives Cardiac abnormalities are among the most common and complex risk factors of pediatric acute ischemic stroke (AIS). Although endovascular treatment (EVT) is increasingly used in children, uncertainty persists regarding its safety and effectiveness in pati...