Université Sorbonne Nouvelle

Split Selves, Alienated Subjects: Mr. Robot and Severance Against Corporate Capitalism

Mr. Robot (Sam Esmail, 2015-2019) and Severance (Dan Erickson, 2022-) portray corporations as a capitalist structure that is simultaneously formative, dehumanizing, and antagonistic. Rather than reducing capitalism to an external structure, these series also present it as an inte...

Systemic anticancer therapy for refractory malignant bowel obstruction in advanced cancer patients: a retrospective cohort study

Objectives Malignant bowel obstruction (MBO) is a common but severe complication of advanced cancer. The role of systemic anticancer therapy in patients with inoperable MBO remains poorly defined. This study aimed to assess the efficacy of systemic anticancer therapy in this sett...

An optimized construction of lie algebra generator pools for variational quantum eigensolvers in chemistry

Abstract Lie algebras are essential mathematical structures used in physics to describe sets of quantum operators. Identifying a minimal set of generators to construct these algebras is a central challenge. The traditional search for such generators relies on greedy construction...

Sex-related variability of white-matter tracts is robust to tractography methodology

Abstract Diffusion tractography is the prominent in-vivo technique to study and investigate white-matter pathways in the human brain. While tractography is a powerful method, recent work suggests that different tractography methods can produce strikingly different representations...

Design and analytical validation of Nexthyro 2.0, a custom next-generation sequencing panel integrating DNA mutation profiling and RNA fusion detection for routine thyroid pathology specimens

Abstract The increasing role of molecular testing in thyroid pathology, from the pre-operative stratification of indeterminate fine-needle aspiration (FNA) categories to the management of advanced carcinomas, has prompted the development of institution-specific custom NGS solutio...

Evaluating the Validity of Model Organisms: A Review and a New Framework for Biologists

Model organisms are central to biological research. Living organisms are models in the sense that the knowledge gained from their study is meant to be generalized. For example, experiments conducted on Drosophila or nematodes bring general knowledge on phenomena such as cell migr...

Effective integration of Lie type algebras

Abstract This is a short survey on the recent developments made in the integration theory with effective formulas of algebraic structures stronger or higher than Lie algebras. This article is part of the theme issue ‘Derived Lie algebras in geometry and topology’.

Guidelines for Studying Mutagenesis in Quiescent Schizosaccharomyces pombe

All living organisms can enter a non-dividing state known as quiescence, which often functions as a survival strategy. In many cases, quiescent cells retain the ability to re-enter the cell cycle when conditions become favorable. Therefore, preserving the integrity of non-dividin...