Université Moulay Ismail de Meknes

A Dual-Stage Metaheuristic-Adam Optimization Framework for Structural LSTM Pruning: Application to Solar Energy Forecasting

Long short-term memory (LSTM) networks, a specialized class of Recurrent Neural Networks (RNNs), excel at capturing temporal dependencies in time-series data but face significant performance trade-offs due to manual architectural design and parameter redundancy. This study introd...

Phenolic Profiling and OECD-Guided Acute and Subacute Oral Toxicity Assessment of Cannabis sativa L. Seed Hydroethanolic Extract

Cannabis sativa L. seeds have been traditionally used in Moroccan folk medicine and are increasingly recognized as a valuable source of nutrients and bioactive phytochemicals with promising therapeutic properties. Despite their widespread traditional and nutritional use, scientif...

Surrogate‐Assisted Multi‐Objective Optimization of an Axial‐Flow Ventricular Assist Device Rotor Using CFD , Hybrid Surrogates, Sobol Analysis, and MOPSO

ABSTRACT Background This study presents a surrogate‐assisted workflow for multi‐objective optimization of an axial‐flow ventricular assist device (VAD) rotor using 4809 steady‐state CFD simulations spanning six geometric variables. Methods Repeated learning‐curve analysis and bla...

Cluster headache care gaps among primary healthcare physicians in the Middle East, North Africa, and Türkiye: a multinational study

Cluster headache is one of the most severely disabling primary headache disorders and is frequently associated with diagnostic delay, inappropriate treatment, disability, and substantial psychosocial burden. Because primary healthcare (PHC) physicians are commonly the first point...

Hypobaric hypoxia at 3,466 m suppresses hepatic bile acid metabolism and remodels the tumor lipidome in mice

Abstract Background Systemic hypoxia induces whole-body metabolic adaptation, but its impact on tumor metabolism and hepatic bile acid (BA) pathways remains poorly defined. Methods We investigated how high-altitude (HA) hypobaric hypoxia at 3,466 m affects tumor growth, tumor lip...

Development and investigation of a NiO/ZnO@PPy-modified glassy carbon electrode for electrochemical sensing of metronidazole in environmental samples: Experimental and DFT studies

Metronidazole (MTZ) is widely prescribed as an antimicrobial drug, and its extensive use in animal farming has led to its accumulation in the environment, posing significant risks to human health and the environment. In this study, nickel and zinc oxide (NiO/ZnO) composite materi...

Biological Activities and In Silico Molecular Docking of an Aqueous Extract of Nigella sativa L. Seeds: A Focus on Antioxidant, Cytotoxic, and Diuretic Effects

Background: Nigella sativa L. is a medicinal plant widely recognized for its diverse pharmacological properties. This study aimed to evaluate the antioxidant, diuretic, and cytotoxic effects of an aqueous seed extract and its effects on selected biochemical parameters in rats. Th...

Photocatalytic performance of the two-dimensional material ZnGeSeO for the hydrogen evolution reaction: A first-principles study

The photocatalytic production of green hydrogen (H 2 ) through water splitting offers a sustainable pathway to convert solar renewable energy into storable chemical fuel while reducing environmental pollution. In this study, first-principles density functional theory calculations...

Of Mimicry and Use in Sustainability Reporting: A Multi‐Method Analysis of ISSB Adoption Intention in Morocco

ABSTRACT This study examines ISSB sustainability reporting standards adoption intention in Morocco by addressing a central theoretical problem: why similar institutional pressures lead to heterogeneous adoption outcomes. We argue that external pressures translate into adoption in...

Synthesis of low-cost hierarchical zeolite 13X structure from abundant natural bentonite for efficient adsorption of polyphenols from olive mill wastewater

Olive mill wastewater (OMW), rich in polyphenols, poses environmental challenges due to toxicity and biodegradation resistance. This study synthesized Zeolite 13X from natural bentonite via alkaline fusion at 550 °C with 2.0 M NaOH and hydrothermal treatment at 100 °C for 48 h. X...

Assessment of groundwater quality through hydrochemical and spatial analysis for domestic and agricultural uses

Abstract Groundwater plays a crucial role in Southeastern Morocco, where arid climate conditions, recurrent droughts, and increasing agricultural demands make it the primary source of water for domestic and irrigation purposes. In the absence of previous studies on the Bouanane w...

Tolerance-aware robust ranking of ventricular assist device rotor designs using strict feasibility and percentile-based criteria

Manufacturing variability can alter the hydraulic and hemocompatibility performance of a ventricular assist device (VAD) rotor even when the nominal design is computationally optimal. This study presents a surrogate-assisted robust-design workflow for a rotary VAD using a CFD-der...

A finite element method for analyzing the free vibration of tapered functionally graded porous (FGMP) arches with point masses

This study examines the linear free vibration of a linearly tapered circular arch made of functionally graded porous material and carrying a concentrated mass at an arbitrary curvilinear location. Both uniform and non-uniform through-thickness porosity distributions are considere...

Finite Element Simulation of Dimensional Shrinkage and Residual Stresses in Material Extrusion of a Highly Filled Metal-Polymer Feedstock (17-4PH)

This preprint presents a staged thermo-mechanical finite element model of the printing, cooling, and detachment stages of material extrusion (MEX) for a highly filled 17-4PH stainless-steel feedstock (95.5 wt.% metal loading, paraffin-wax/stearic-acid binder). Extending the seque...

Numerical Simulation of the Bending Behavior of a Topologically Optimized Structure Printed in ABS by FDM: G-Code-Driven Mapping of Local Material Orientations

This preprint presents an original dual-branch numerical pipeline for simulating the bending behavior of an MBB (Messerschmitt-Bölkow-Blohm) beam, topologically optimized using the SIMP method and manufactured in ABS by fused deposition modeling (FDM). Starting from a single G-co...

Numerical Simulation of the Bending Behavior of a Topologically Optimized Structure Printed in ABS by FDM: G-Code-Driven Mapping of Local Material Orientations

This preprint presents an original dual-branch numerical pipeline for simulating the bending behavior of an MBB (Messerschmitt-Bölkow-Blohm) beam, topologically optimized using the SIMP method and manufactured in ABS by fused deposition modeling (FDM). Starting from a single G-co...

A hybrid global maximum power point tracking of a PV-Battery system under complex partial shading conditions using horse herd optimization algorithm and a variable step size perturb and observe

Photovoltaic (PV) arrays are sensitive to variable environmental conditions, which requires continuous regulation to maximize power, this makes maximum power point (MPP) trackers an essential element in every PV generation system, in particular, when PV arrays are under nonunifor...

Service-Life Prediction of Core Inserts Under High-Volume Plastic Injection Molding Conditions

High-volume injection molding systems for plastic part production operate under severe thermo-mechanical loading repeated at high production rates. Therefore, premature breakage of hot-work tool steel core inserts directly interrupts production continuity and creates a recurrent...