Université de Limoges

Hackathon on predictive modelling in systems pharmacology: design, implementation, and outcomes

Background The growing availability of multi-omics data and machine learning methods creates both an opportunity and a challenge for the systems pharmacology community: the opportunity to model drug action at unprecedented mechanistic resolution, and the challenge of equipping a...

Global Incidence of All-Cause Dementia

Importance Global dementia incidence estimates are limited by underrepresentation of low- and middle-income countries and heterogeneous analytic methods. Due to these limitations, true understanding of the global dementia landscape remains incomplete. Objective To identify dement...

Parallel-in-Time Preconditioning for Time-Dependent Variational Mean Field Games

Abstract We study the numerical approximation of a time-dependent variational mean field game system with local couplings and either periodic or Neumann boundary conditions. Following a variational approach, we employ a finite-difference discretization and solve the resulting fin...

Integrating Bulk and Molecular Analyses with PCA to Elucidate OM Dynamics in Treated Sludge: Insights for Sustainable Waste Management

Abstract Effective sludge treatment is essential for sustainable waste management, addressing environmental protection, public health, and resource recovery objectives. This study investigates the stabilization dynamics of five treated sludge products—raw thickened, digested, dri...

Methods for assessing the acquisition of pharmaceutical care skills among students and pharmacists: a scoping review

Abstract Introduction Competency-based education is central to preparing health professionals for complex, patient-centered practice. In clinical pharmacy, assessing medication-related care competencies remains challenging due to a lack of standardized frameworks adaptable to dig...

Occurrence and Genomic Characterization of Listeria monocytogenes ST121 in Animal-Derived Food Samples from Bejaïa, Algeria

Listeria monocytogenesis an important foodborne pathogen that can cause severe invasive disease in vulnerable populations. This study assessed the occurrence of L. monocytogenes in animal-derived foods collected in Bejaïa, Algeria, and characterized recovered isolates using whole...

Generative surrogate modelling for the efficient design optimization of an RF component

Accurate and efficient design of millimeter-wave components is critical for sixth-generation (6 G) wireless systems, particularly at the D-band where low-loss interconnects are required. Vertically aligned carbon-nanotube (VACNT)–based air-filled waveguides (AFWGs) have recently...

Performance of pseudonymization methods applied to hospital documents in the context of health data warehouses

Introduction The development of health data warehouses (HDWs) in France raises concerns about personal data protection. Regulations require health research to use anonymized or pseudonymized data. This study evaluates a document pseudonymization tool developed by Assistance Publi...

Pedicled Total-Leg Fillet Flap for Salvage Coverage of a Combined Pelvic and Proximal Femoral Defect After High-Voltage Electrical Burn: Technical Considerations, Limitations and Focused Review

Etienne L E Joly, Valentin David, Xavier Pichon, Benoit Chaput, Silvia Gandolfi; Pedicled Total-Leg Fillet Flap for Salvage Coverage of a Combined Pelvic a

Engineering Ultra‐Low Fe or Ni Loading in Polymer Derived SiCN(O) Fibre Mats: Exploring the Performance towards Alkaline OER

ABSTRACT In this study, Fe or Ni‐anchored silicon carbo(xy)nitride (SiCN(O)) fibre mats were synthesized via the polymer‐derived ceramics (PDC) approach to investigate their electrocatalytic performance toward alkaline OER. The resulting fibrous‐supported pre‐catalysts formed por...

Association Between Therapeutic Education Delivered by a Community Post-Stroke Rehabilitation Team and Improvement in the Frenchay Activities Index: A Retrospective Cohort Study

Background Social participation is frequently impaired after stroke. Therapeutic patient education (TPE) may promote self-management and community reintegration, but evidence regarding home-based programs delivered by Community Stroke Rehabilitation Teams (CSRTs) remains limited....

From fluid loss to calcification: MRI and CT matrix features in cystic echinococcosis

Abstract Objective To characterize MRI matrix signal and CT calcification patterns across WHO-IWGE stages, compare them with lesion mimicking cystic echinococcosis (CE), and derive an MRI-based subclassification for inactive cysts. Materials and methods This retrospective multice...

Towards a deep-learning genomic tool for risk stratification and diagnostic support in sporadic ALS

Abstract Background A variety of common and rare genetic factors have been implicated in the development of amyotrophic lateral sclerosis (ALS), and the evidence is that a genetic component is present in most affected individuals. However, our current understanding of ALS genetic...

“Trends and future directions in purchasing decisions in supply chain management”: a systematic review and bibliometric analysis from pre-to post-pandemic

Purpose This study uses the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology to critically examine and review existing research on supplier selection in supply chain (SC) management before and after the onset of the pandemic. The study explo...

Adherence and Healthcare Costs Associated with Single-vs Free-Pill Combination of Perindopril-Based Antihypertensive Medications: An 11-Year Follow-Up, Real-World Evidence

BACKGROUND: Short-term studies have demonstrated that single-pill combinations (SPCs) improve adherence, reduce hypertension-related complications, and lower costs; however, long-term benefits remain unclear. This study compared adherence, healthcare resource utilization (HCRU),...