Université Côte d'Azur

Sex of central neurons controls intestinal niche signalling to drive sex differences in stem cell activity and cancer susceptibility

Abstract Sex differences in cancers arising in non-reproductive organs are widespread. While sex hormones and the intrinsic sexual identity of cancer cells are well-established contributors, it is unknown whether other mechanisms are involved. Here, we reveal an unexpected source...

Earliest simultaneous multi-color optical observations of GRB 230328B: from 41 seconds to the host-galaxy identification

Abstract We present a multiwavelength study of the long-duration gamma-ray burst GRB 230328B, combining prompt γ-ray observations with exceptionally early simultaneous optical photometry and extensive X-ray, radio, and host-galaxy follow-up. NUTTELA-TAO began simultaneous g′r′i′...

Rab4b controls hepatic glucose production during fasting through glycophagy

Abstract Hepatic glucose production, essential for maintaining glycemia, is often altered in metabolic-associated fatty liver and glycogen storage diseases. Therefore, understanding the mechanisms that regulate the glucose production by hepatocyte is pivotal. Recent studies have...

Effects of home-based videoconference adapted physical activity on healthy aging

Abstract Aging induces muscle weakness and power decline in older adults, increasing the risk of falls. Adapted physical activity (APA) programs are effective in mitigating these declines. Recent innovations, including videoconferencing, offer alternative delivery modes, but thei...