Universität Greifswald

Vocalizations shape roost defence outcomes in a solitary bat

Individuals commonly compete with others that share their ecological niche, both within and among species. To avoid physical confrontations, individuals can use various types of signals to demonstrate their dominance, including vocalizations. Kerivoula hardwickii is a solitary ba...

Little evidence for cultural differences in automatic imitation

Individuals tend to automatically imitate others' actions. Such imitative behavior is often assumed to be a universal phenomenon. However, most prior research has focused on Western, Educated, Industrialized, Rich, and Democratic (WEIRD) populations, leaving open whether people a...

Relationship between neonatal glutamine supplementation and amino acid profiles, protein synthesis in splanchnic tissues and the plasma metabolome in 5-day-old piglets with low birth weight

The incidence of low birthweight ( LBiW ) piglets, which show impaired growth compared to normal birthweight ( NBiW ) littermates, has increased with litter size. We previously reported that glutamine increased the bodyweight and plasma glutamine concentrations in LBiW piglets, w...

An inducible co-stimulator ligand (ICOSL)-based peptide therapy for proteinuric kidney diseases targeting αvβ3 integrin

Abstract Dysregulated αvβ3 integrin activation in podocytes contributes to proteinuric kidney disease by disrupting podocyte architecture and the glomerular filtration barrier. However, no treatments currently exist that therapeutically target this integrin. We previously identif...

The geometry of gametic dispersal in a flying mammal, Rhinolophus hipposideros

Abstract Dispersal influences population and evolutionary dynamics, in a manner that depends on by which dispersal strategies gene flow occurs. In some species, mating partners move exclusively for mating, dispersing genes but not individuals. This is the case in many bat species...

Mergers Fall Short: Nonmerger Channels Required for Galactic Heavy Element Production

Abstract Since the discovery of the binary neutron star merger GW170817 and its associated kilonova, neutron star mergers have been established as a key production channel for r -process elements in the Universe. However, multiple lines of evidence, including the observations of...

Epitranscriptomic profiling of VSMC phenotypes reveals uridine modifications linked to post-transcriptional regulation

Background The phenotypic plasticity of vascular smooth muscle cells (VSMCs) can modulate atherosclerosis progression. Although several gene regulatory steps towards pro-inflammatory phenotypes have been well-studied, epitranscriptomic changes during this transition and their reg...

What is it Like to Recover From Psychosis? An Interpretative Phenomenological Analysis

Abstract This study aims to explore the lived experience of recovery from psychosis, with a focus on pre-reflective, embodied, and intersubjective aspects. Semi-structured interviews were conducted with six individuals diagnosed with schizophrenia. The data collected were analyze...

From pollen to pixels: Towards spatially meaningful pollen-based vegetation reconstructions across southeastern Australia

Reconstruction of past vegetation underpins understanding of long-term ecosystem and societal change, helping to contextualise present-day patterns in biodiversity, ecosystem trajectories and effective landscape management practices against historical ecosystem states. This is pa...

Enzymatic tailoring of prebiotic oligosaccharides, flavonoids, and terpenoids for enhanced physiological effects

Next-generation functional foods provide a paradigm shift from generalized healthcare to personalized nutrition. Rational design of functional ingredients based on structure-activity relationships is essential for their further development. Because of high substrate specificity a...

Psychotherapy remission prediction models show limited cross-clinic generalizability in routine outpatient care

Abstract Clinical prediction models for psychotherapy outcomes have the potential to assist therapists in planning a patient’s individual treatment, but their clinical utility depends on maintaining predictive performance across settings. We assessed prediction of post-treatment...

Detectability of solid particle injections into the stratosphere with satellite solar occultation instruments

Stratospheric aerosol injections (SAI) have been proposed as a potential climate intervention to mitigate some effects of global warming. This method involves the idea of injecting sulphur dioxide into the stratosphere. Other ideas include the injection of solid particles, like a...

Distinct or similar? Career choice motivation in preservice special education and secondary school teachers

Abstract Career choice motives play a central role in teacher development, professional commitment and retention. Although special education is often assumed to attract individuals with strong pedagogical and altruistic motives and lower extrinsic orientations, empirical evidence...

Learning from model failure: insights from an AI/SHAP-based temporal error decomposition of tracer-aided ecohydrological modelling

Abstract. Process-based models (PBM) have served as testing grounds for hypotheses, being falsified and refined through model evaluation based on temporally complex PBM errors. Yet, conventional evaluation practices (e.g., performance metrics, visual inspection across time series...

Short-read genome skimming enables molecular barcoding of old myxomycete collections

This study evaluates the effectiveness of Illumina-based genome skimming for barcoding myxomycete herbarium collections ranging from 29 to 91 years in age. We successfully retrieved partial sequences of the standard marker gene (nucSSU) in all cases, as well as additional markers...

Timing of PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation

BackgroundApproximately one half of patients undergoing transcatheter aortic-valve implantation (TAVI) have concomitant coronary artery disease. Although percutaneous coronary intervention (PCI) is often performed before TAVI, the preferred treatment strategy has not been establi...

Rapid Two-StepMulticomponent Synthesis and Structure-degradationRelationships of Selective HDAC6 PROTAC Degraders

Abstract This work reports on the development of selective histone deacetylase 6 (HDAC6) degraders based on a peptoid scaffold. Structure-based design identified the isocyanide-derived cap region as suitable exit vector for linker attachment, enabling rapid generation of CRBN-rec...

Webinars about child and adolescent psychiatry can support professionals in war-affected regions: lessons from the ESCAP-Ukraine webinar initiative

War has a profound impact on child and adolescent mental health and service provision. This requires creative internationally supported response to strengthen professional capacity in trauma care, psychosocial support and evidence based clinical practice in child and adolescent p...