Universitas Sumatera Utara

Ferroptosis in Anthracycline Cardiotoxicity: Mechanisms, the Cardioprotection Paradox and the Limits of Single‐Pathway Thinking

ABSTRACT Anthracyclines remain among the most effective cytotoxic drugs, but their cumulative cardiotoxicity limits dosing and threatens survivors with heart failure. The discovery that doxorubicin kills cardiomyocytes substantially through ferroptosis—an iron‐dependent, lipid‐pe...

Poison control centre in Indonesia: What are we waiting for?

In this letter, we present a case that drew significant public attention in Indonesia. The case involved a young boy who was bitten by a banded krait while sleeping. He was taken to a hospital, but due to delayed management, he eventually passed away. This case highlights the com...

Propolis-bovine hydroxyapatite scaffold, with or without glutaraldehyde crosslinking, enhances bone healing: An experimental study on femoral small-sized defect model

Objectives: This study evaluated whether bovine hydroxyapatite (BHA) combined with propolis, with or without glutaraldehyde (GTA) crosslinking, enhances bone healing in a rat femoral small-sized defect model. Methods: Forty-eight male Wistar rats were allocated into four groups:...

STRUCTURAL AND ELECTROCHEMICAL PROPERTIES OF CHITOSAN/GQDS/ZIF-67 COMPOSITES

The development of materials based on Zeolitic Imidazolate Framework-67 (ZIF-67) has attracted attention in the field of electrochemical sensors due to their large surface area, good porosity, and the presence of Co²⁺ active sites, which play a role in enhancing electrochemical a...