Università degli Studi di Enna Kore

Adult attachment, death anxiety, representation of death, and depression, anxiety, obsessive-compulsive, and somatic symptoms in early emerging adulthood: a moderated mediation model

Death anxiety has been increasingly recognized as a transdiagnostic factor associated with a wide range of internalizing symptoms, yet the psychological mechanisms linking existential concerns to psychopathology remain incompletely understood. Drawing on attachment theory and exi...

Machine Learning-Based Classification of Retinitis Pigmentosa from Color Fundus Images: A Reproducible Benchmark and Screening-Oriented Pipeline

Retinitis pigmentosa (RP) is a rare inherited retinal disorder in which fundus changes may be subtle and heterogeneous, limiting detection from color fundus images. This study evaluated multiple machine learning architectures for binary-RP versus healthy-control classification, a...

Real-World Antibiotic Strategies for Multidrug-Resistant Pseudomonas aeruginosa: Evidence from the Italian SUSANA Multicentre Study

Background/Objectives: Multidrug-resistant (MDR) Pseudomonas aeruginosa pneumonia and bloodstream infections (BSI) remain challenging because of their severity, limited therapeutic options, and high mortality, despite the availability of novel β-lactam-based agents. We aimed to d...

Personalized Medicine for the Management of Non-Communicable Diseases (NCDs)

Non-communicable diseases (NCDs) are the leading cause of death worldwide and are among the major drivers of healthcare expenditure, particularly in societies undergoing progressive population aging [...]

Concurrent Assessment of Micro- and Nanoplastics and Bisphenol A in Non-Dialysis Chronic Kidney Patients and Hemodialysis Patients: Results from a Cross-Sectional Human Biomonitoring Study Focusing on Sex-Related Patterns

Patients with chronic kidney disease (CKD), particularly those receiving hemodialysis (HD), may be more vulnerable to exposure to micro- and nanoplastics (MNPs) and bisphenol A (BPA) because of impaired renal clearance and frequent contact to plastic-based medical devices. This s...

Comparative Efficacy Of Different Computer-Aided Detection Products in Colonoscopy: A Network Meta-Analysis Of Randomized Controlled Trials.

Background and aims: Multiple computer-aided detection (CADe) systems have been developed to improve adenoma detection during colonoscopy, but their comparative efficacy and consistency of effect remain uncertain. This network meta-analysis aimed to compare the efficacy of differ...

Pyrroloquinoline Quinone and NAD+ Metabolism in Glaucoma: A Molecular Rationale for Combined Neuroprotection

Glaucoma is the leading cause of irreversible blindness worldwide and a paradigmatic age-related neurodegenerative disease in which retinal ganglion cells (RGCs) are selectively lost through mechanisms that extend beyond intraocular pressure. Age-dependent NAD+ depletion in RGCs,...

Data-Driven Ensemble Machine Learning for Multi-Horizon Microalgal Bioprocess Forecasting

Microalgal bioprocesses increasingly rely on predictive modelling to support automated control and reduce the cost of laboratory experimentation. Yet, the scarcity of high-quality datasets and the nonlinear nature of microalgal growth severely limit the accuracy and robustness of...

Implant-Supported and Conventional Dentures: A Meta-Analysis in Older Adults

Statement of problem Edentulism is highly prevalent among older adults, with approximately 30% of adults aged ≥60 years affected by complete tooth loss in at least one dental arch. Conventional complete dentures (CCDs) often provide suboptimal retention and stability, negatively...

Detailed study of non-equilibrium characteristics of quasi-neutral TNSA plasmas

In an experiment performed in November 2022 at the petawatt (PW) laser facility at Vega III located in Salamanca-Spain, we have studied the successful production of several radioisotopes using protons accelerated by the Target Normal Sheath Acceleration (TNSA) mechanism (Rodrigue...