Universidade Nova de Lisboa

Glycome remodeling programs pathogenic γδ T17 cell responses in autoimmunity

Glycans play fundamental roles in T cell biology; however, the glycome landscape of γδ T cells remains to be unlocked. Despite the growing importance of γδ T cells in host defense, tissue homeostasis, and diseases, the glycosylation mechanisms guiding their activation, commitment...

Naming Nature: Exploring the Flexibility of Ethnoclassifications of Mammals in Guinea-Bissau

Naming non-human beings enables humans to relate to and establish relationships with different organisms, and is a way of classifying the world around them. Understanding how different groups of people carry out ethnoclassifications of non-human animals is important for establish...

Moving Mass Problem—Analytical Approximation of Transient Solution on Infinite Two-Layer Model

The problem of moving inertial objects traversing simplified models of railway tracks has an analytical solution in the transformed domain under the assumptions of linearity and longitudinal homogeneity of the model. However, the time-domain response usually requires numerical in...

Ohmic Heating as a Strategy for Upcycling PET Plastic Waste for New Supramolecular Structures

The massive accumulation of poly(ethylene terephthalate) (PET) plastic waste poses a significant global environmental challenge, requiring the development of more sustainable upcycling strategies. This study investigated the alkaline hydrolysis of PET flakes to recover terephthal...

Urban Brownfields Regeneration: A European Perspective and Application to Portugal

The decline of industrial activity across Europe has produced extensive brownfield landscapes that today constitute both a challenge and a strategic opportunity for urban regeneration and the promotion of new sustainable urbanisation models. In Portugal, the regeneration of urban...

Seawater pH Measurement: A Critical Metrological Assessment of Operational Scales and the Unified pH Scale

Ocean acidification, driven by rising anthropogenic CO2, causes a measurable decrease in seawater pH with consequences for marine ecosystems. Accurate, traceable pH measurement is essential for ocean monitoring sensors. This critical review examines five pH scales: the IUPAC acti...

Coupled U–Pb geochronology of inherited and detrital zircon in the Iberian Massif: insights into its deep structure and geodynamic evolution

Abstract The combined use of detrital and inherited zircon U-Pb age spectra provides new insights into the crustal evolution of the Iberian Massif as part of the North Gondwana margin. In the Ossa–Morena Zone (OMZ), Ediacaran detrital zircon populations are dominated by Pan‑Afric...

Natural History of Rare Tumor Risk Syndromes: A Scoping Review to Inform Cost-Effectiveness Models

Background Hereditary cancer syndromes account for approximately 10% of all cancers. Many of these, classified as rare tumor risk syndromes (RTRS), lack comprehensive data on natural history, lifetime cancer risk, and the long-term impact of surveillance. These evidence gaps limi...

Serotype-independent inhibition of S. pneumoniae by SMiTE, a commensal-derived bacteriocin

ABSTRACT Streptococcus pneumoniae remains a leading cause of disease despite widespread vaccination, highlighting the need for serotype-independent strategies. We recently identified commensal streptococci that produce bacteriocins with anti-pneumococcal activity. Here, we evalua...

Engineering a Modular Bacterial Galactose Oxidase through CBM Recombination and Second-Shell Substitutions

Abstract Galactose oxidases (GalOxs) are copper-radical enzymes that selectively oxidize primary alcohols, yet the structure–function determinants governing their catalytic efficiency and substrate scope remain incompletely understood, particularly in bacterial enzymes. Here, we...

Public health workforce reform in Abu Dhabi: a pathway to evidence-based policy and global standards alignment

Reforming the public health workforce in Abu Dhabi and across the United Arab Emirates (UAE) became increasingly urgent during and after the COVID-19 pandemic, alongside wider pressures from evolving public health challenges and health-system transformation. A mixed-methods study...

Why do people migrate irregularly? Evidence from a lab-in-the-field experiment in West Africa

Irregular migration to Europe by sea, though risky, remains one of the most popular migration options for many Sub-Saharan Africans. This study examines the drivers of irregular migration decisions using an incentivized lab-in-the-field experiment in rural Gambia, the African cou...

The law won? – Maritime courts, the labour market and seamen's litigation in early modern Holland and Zeeland (1641–1692)

In the second half of the seventeenth century, three cities in Holland and Zeeland established maritime courts. While their competence included adjudication over all maritime disputes, they were specifically designed to resolve disputes between crews and their skippers over wages...

European joint programme HBM4EU - Bridging science and policy: experiences and lessons learned from the key partners in the scientific steering of the initiative

The European Joint Programme HBM4EU was established to address politically relevant questions on chemical risks to public health through a targeted human biomonitoring research programme. Running from 2017 to 2022, it was co-financed by the EU's Horizon 2020 Research and Innovati...

Bridging skills gaps: how micro-credentials reshape sustainable development learning in higher education

Abstract Micro-credentials (MCs) are gaining traction in higher education as essential tools for advancing sustainable development (SD). These short, focused courses provide learners with specific skills and knowledge related to sustainability, enabling them to address pressing g...

Tetranuclear Copper Cluster of N2O Reductase: A Distinctive Copper–Sulfur Metallocluster

Abstract Copper is an essential element involved in several cofactors and organometallic compounds used as catalysts. Although most biological copper centers contain one to three copper ions, nature has evolved a unique tetranuclear copper–sulfur cluster that has attracted the at...

Edge-Aware Remote Sensing Image Super-Resolution via Kolmogorov–Arnold Networks

Remote sensing image super-resolution aims to reconstruct high-quality spatial details from low-resolution observations, which is essential for land-cover interpretation, object detection, and downstream geospatial analysis. However, existing convolutional neural network (CNN)- a...

The role of deontological morality in shaping demand within the sharing economy

This study examines how deontological and consequentialist appeals in Airbnb host self-descriptions relate to trust-related attention and marketplace performance. Study 1 combines a five-city listing panel with third-party New York property-month records; Study 2 analyzes a behav...

Promoting sustainability teaching and learning in HEI through the ecological footprint concept

Purpose Higher education institutions (HEIs) play a key role in democratising quality education for sustainability, for all. This study aims to present the outcomes of implementing the EUSTEPs Sustainability Module, which acquaints HEI students with sustainability concepts in an...

Worlds of Clay: Metamarkers between Matter, Symbol and Computation

Repository accompanying Worlds of Clay: Metamarkers between Matter, Symbol and Computation, prepared for submission to Interface Focus. Version 1.2.0 records the revised English manuscript, its rendered PDF and standalone LaTeX export, bibliography, citation style, and photograph...