Universidade Federal do Ceará

Effect of slaughter weights on some meat quality traits of Santa Inês lambs in a feedlot

Context The growing demand for more tender and healthy meat requires more precise parameters. Therefore, defining the ideal slaughter weight for sheep is crucial to strike a balance between productive performance and meat quality. Aims In this context, we aimed to evaluate the ef...

Synthon-Based Crystal Engineering of Mebendazolium Tosylates: Solid-Form Design, Structure−Property Relationships, and Enhanced Solubility from Experimental and DFT Studies

Abstract Salt formation is a well-established crystal engineering strategy to modulate the physicochemical and pharmacokinetic properties of active pharmaceutical ingredients. In the case of mebendazole (MBZ), a broad-spectrum anthelmintic, this approach has been successfully emp...

Thermal Cycle–Microstructure–Property Relationships in Rail Steel Heat‐Affected Zone Simulated by Gleeble

This study investigates the microstructural evolution and mechanical response of premium rail steel subjected to heat‐affected zone (HAZ) thermal cycles representative of flash butt welding (FBW). Dilatometry experiments were performed using a Gleeble thermomechanical simulator....

Core–Shell Upconversion Platform Based on an Amino-Functionalized ZIF-8 with a Covalently Anchored Ruthenium Nitrosyl Complex for Controlled Release of Nitric Oxide in Biological Media

Abstract The development of nitric oxide (NO) donor agents capable of controlled NO release upon light irradiation in the biological window is relevant for phototherapies. The cis-[Ru(dc-bpy)2(SO3)(NO)]+ complex (dc-bpy = 2,2′-dicarboxybipyridine) is synthesized and anchored onto...

Isoforms of cysteine peptidases and osmotins instead of chitinases and peptidase inhibitors drive antifungal activity but occur as distinct isoforms in latex and callus tissues of Calotropis procera

MAIN CONCLUSION: Peptidases and osmotins are the primary determinants of antifungal activity, and their expression is tightly linked to tissue specialization in Calotropis procera plants. This study investigated whether callus cultures of two Apocynaceae species, Calotropis proce...

Data and analysis code for "Peripheral immune biomarkers in bipolar disorder: a pathway-focused systematic review and meta-analysis of the Th17 axis"

Complete data and analysis package for a systematic review and meta-analysis of peripheral immune biomarkers in bipolar disorder, focused on the interleukin-23/T-helper-17 axis (PROSPERO CRD420261434475). The deposit contains the extraction layer (one row per reported group stati...

TELAPSI: Development and Content Validation of a Digital Learning Object Based on Cinematic Narratives for Schizophrenia Education in Medicine

Abstract Objective To develop and evaluate TELAPSI, a freely accessible bilingual digital learning object that supports faculty in teaching about schizophrenia through curated cinematic scenes linked to psychopathological descriptions and structured lesson plans. Methods A method...

New Insights About the Psychometric Properties of the Montgomery‐Asberg Depression Rating Scale

ABSTRACT Objectives This study aimed to comprehensively investigate the psychometric properties of the Montgomery‐Åsberg Depression Rating Scale (MADRS) in a sample from Northeast Brazil. Methods Data were obtained from a cross‐sectional study of 303 participants with depressive...

Stable isotopes and metals and metalloids in the smallest Megamouth Shark (Megachasma pelagios) reported to date from the Atlantic Ocean

), likely reflecting ocean-basin-specific biogeochemical baseline and mainly organic chemical forms typical of deep-water elasmobranchs. Finally, the findings reinforce the importance of continuous monitoring in the Atlantic Ocean to expand and consolidate knowledge on the ecolog...

L-Glutamic acid production by lactic acid bacteria from Brazilian fermented foods: screening, optimization, and probiotic-related properties of Limosilactobacillus fermentum CCMA 0205

L-Glutamic acid (L-Glu) is an amino acid of considerable industrial importance owing to its widespread application as a flavor enhancer and its increasing use in food biotechnology. The identification of novel microbial producers and the optimization of fermentation processes rem...

Physical therapy care utilization and associated sociodemographic and clinical factors among noncommunicable diseases in the brazilian population: A cross-sectional, population-based study

INTRODUCTION: Noncommunicable diseases (NCDs) are currently the leading cause of disability worldwide. In Brazil, NCDs are among the top 10 causes of disability-adjusted life years (DALYs). A better understanding of the profiles of patients who frequently use physical therapy is...

Chemical Fingerprinting for Authentication and Compositional Characterization of Cocos nucifera Bee Pollen

Abstract Bee pollen produced by Apis mellifera is formed by the agglutination of floral pollen grains with nectar and bee secretions. Monofloral or dominant bee pollen generally exhibits a more consistent chemical composition and quality. In this study, coconut (Cocos nucifera) b...

Migraine Across the Menopausal Transition: Clinical Trajectories, Biological Mechanisms, and Management—a Scoping Review

Abstract Background Migraine is a common and disabling neurological disorder among women, and hormonal variability may influence disease expression during midlife. However, migraine trajectories across the menopausal transition remain heterogeneous and incompletely characterized....

Maximum entropy modeling of spin-glass behavior in random lasers

We investigate random-laser (RL) emission fluctuations using a Maximum Entropy (MaxEnt) framework. Experimental spectra across pump powers are binarized into spin-like variables, and a MaxEnt model is inferred from single-wavelength magnetizations and pairwise correlations. The r...

Next-generation CAR-T therapy for malignant brain tumors: latest updates from the 2026 AACR Annual Meeting

The 2026 AACR Annual Meeting showcased rapid progress in chimeric antigen receptor (CAR) T-cell therapy for malignant brain tumors. This correspondence synthesizes 12 clinical and translational abstracts addressing early efficacy, resistance mechanisms, target discovery, and next...

Subchronic Exposure to Cannabis‐Based Nanoemulsions Induces Histopathological and Molecular Alterations in the Rat Submandibular Gland

ABSTRACT The increasing therapeutic incorporation of cannabis has expanded phytocannabinoid application, yet peripheral adverse effects like xerostomia raise concerns regarding emerging biotechnological formulations. This study evaluated the effects of cannabis‐based lipid nanoem...

Combining genomic prediction and multi-trait indices through stochastic simulations: do index type and deployment order affect genetic gain?

Abstract Genomic selection (GS) has transformed plant breeding by enabling early selection and potentially reducing cycle length, but how to integrate GS with classical multi-trait selection indices remains unclear. We used stochastic simulations to compare seven strategies combi...

Self-Efficacy and Perceived Study-Related Difficulties in Early Medical Training: A Correlational Study

Abstract Self-efficacy is a relevant psychosocial variable in medical education because it may influence how students organize their learning, persist when facing academic demands, and cope with perceived difficulties. This study analyzed the relationship between perceived self-e...

ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review

Abstract Ataxia Telangiectasia Mutated ( ATM ), a central kinase in the DNA damage response, is recurrently altered across these disorders, including myelodysplastic neoplasms (MDS), acute myeloid leukemia (AML), and myeloproliferative neoplasms (MPN), yet its clinical significan...

From Waste to Resource: Upcycling Spent Coffee Grounds into Biochar Functionalized with CaFe2O4 for Phosphate Removal

Abstract Eutrophication caused by excess phosphorus in water bodies represents a significant environmental challenge, requiring efficient, selective, and sustainable technologies for its mitigation. In this study, a magnetic biochar (BiMag) was developed through the valorization...