Universidade Federal de Pernambuco

ATR-FTIR Spectroscopy Combined with Machine Learning Enables Detection of Schistosomiasis-Associated Biochemical Signatures in Human Serum

Abstract Schistosomiasis, caused by Schistosoma mansoni, remains a major public health burden in endemic regions, demanding rapid and reliable diagnostic strategies. Here, we report a label-free diagnostic platform based on attenuated total reflectance Fourier transform infrared...

Evaluation of the Inhibitory Effects of Aqueous Extracts of Rhynchospora nervosa (Vahl) Boeckeler on the Germination and Initial Development of Cowpea (Vigna unguiculata (L.) Walp.)

Rhynchospora nervosa is a weed associated with infestations in economically important agricultural crops in several regions of Brazil. In this context, the present study aimed to perform phytochemical screening and evaluate the allelopathic effects of aqueous extracts from the ae...

MicroRNAs in autoimmune connective tissue diseases: Pathogenic roles, clinical implications, and therapeutic potential

MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression involved in immune homeostasis, inflammation, fibrosis, and vascular remodeling. Their dysregulation has been increasingly implicated in the pathogenesis of autoimmune connective tissue diseases (ACTDs)...

Core–Shell Upconversion Platform Based on an Amino-Functionalized ZIF-8 with a Covalently Anchored Ruthenium Nitrosyl Complex for Controlled Release of Nitric Oxide in Biological Media

Abstract The development of nitric oxide (NO) donor agents capable of controlled NO release upon light irradiation in the biological window is relevant for phototherapies. The cis-[Ru(dc-bpy)2(SO3)(NO)]+ complex (dc-bpy = 2,2′-dicarboxybipyridine) is synthesized and anchored onto...

Matrix Acidizing in Dolomitic Rocks: Wormhole Development and Injection Performance Analysis

Abstract Matrix acidizing is widely used to improve the productivity of carbonate reservoirs, particularly those with significant dolomitic content, which account for a substantial fraction of global hydrocarbon reserves. In this study, the pore volume to breakthrough (PVbt) beha...

Upregulation of cellular exhaustion-related genes and CD4 + T cell disturbances in immunological non-responders on antiretroviral therapy

Abstract Antiretroviral therapy suppresses HIV replication, but 10–40% of people living with HIV do not reconstitute CD4 + T cell counts despite viral suppression. Cellular exhaustion and alteration in the frequency of CD4 + T cell subsets are mechanisms involved in immunological...

Human dimensions of protected areas: a systematic review of the social-ecological effects of legal restrictions on local communities

Legal restrictions associated with protected areas can act as anthropogenic disturbances in social-ecological systems, altering relationships among communities, territories, and resources. This study examined how the scientific literature documents these effects by investigating...

Essential oil from Piper aduncum L. leaves exhibits analgesic and anti-inflammatory activity in mice

Piper aduncum L. is a medicinal plant whose essential oil is rich in bioactive constituents, particularly dilapiol, and has attracted interest because of its diverse pharmacological properties. However, its anti-inflammatory, antipyretic, and antinociceptive activities and the me...

Persistence of leprosy in northeast Brazil: epidemiological characterization and spatial distribution over a decade.

Leprosy is an infectious disease caused by Mycobacterium leprae, predominantly affecting vulnerable populations. This study analysed the spatial and spatiotemporal distribution of leprosy cases in northeast Brazil and their epidemiological characteristics. An ecological study use...

Spatially explicit modeling of future land use and land cover dynamics in the São Francisco River Basin, Brazil

Future land use and land cover (LULC) changes in major Brazilian river basins may pose substantial challenges for water resource management by altering streamflow regimes, reducing water availability, affecting ecosystem services, and increasing pressure on vulnerable hydrologica...

Effect of different cariostatic agents on the surface roughness and color change of CAD–CAM‐milled restorative materials: An in vitro comparative study

Abstract Purpose To evaluate the influence of different cariostatic agents: 38% silver diamine fluoride (SDF), 38% SDF + potassium iodide (RS), and nano silver fluoride (NSF) compared with distilled water (control), on the surface roughness and color change of CAD–CAM‐milled rest...

Origin of Thermal Nonlinear Refraction in Alcohols Revealed by Spatial Self-Phase Modulation under Excitation at 1560 nm

Abstract We investigated the relationship between molecular structure and nonlinear thermal responses of alcohols with different numbers of carbon atoms in their main chains using spatial self-phase modulation experiments at 1560 nm. The studied materials included the following a...

Successful Combined Therapy for Post-Orgasmic Illness Syndrome: A Case Report.

Post-Orgasmic Illness Syndrome (POIS) is a rare con-dition characterized by flu-like symptoms after ejacula-tion, lasting several days and impairing quality of life. A 62-year-old man developed POIS after percutaneous ep-ididymal sperm aspiration, with symptoms lasting seven days...

Maximum entropy modeling of spin-glass behavior in random lasers

We investigate random-laser (RL) emission fluctuations using a Maximum Entropy (MaxEnt) framework. Experimental spectra across pump powers are binarized into spin-like variables, and a MaxEnt model is inferred from single-wavelength magnetizations and pairwise correlations. The r...

Morphoanatomical and Histochemical Description of Vegetative Organs and Phytochemical Characterization of Leaf Extracts of Plantago major

Aim of study: This study aims to conduct a morphoanatomical and histochemical analysis of the vegetative organs, as well as a phytochemical assessment of leaf extracts of Plantago major. Area of study: Samples were collected from Muribeca, Municipality of Jaboatão dos Guararapes,...

Differential Diagnosis of Mucopolysaccharidoses Types I, II , III , IVA , and VI Through Analysis of Leukocytic Inclusions

ABSTRACT Mucopolysaccharidoses (MPS) are lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs), which can lead to cytoplasmic alterations in leukocytes. The objective of this study was to characterize leukocyte inclusions in patients with diff...

Absolute Primary Nanothermometry Using Individual Stark Sublevels of Rare-Earth-Doped Crystals

Abstract We present two independent optical methods for absolute primary thermometry using rare-earth-doped nanoparticles. Both approaches rely exclusively on the internal energy levels and population dynamics of the dopant ions, eliminating the need for external temperature refe...

Psychometric evaluation of the Brazilian version of the Postpartum Specific Anxiety Scale – Research Short-Form for Global Crises (PSAS-BR-RSF-C)

Abstract Purpose Anxiety symptoms are highly prevalent during the postpartum period; however, validated instruments to measure postpartum-specific anxiety in Brazil are lacking. This study aimed to evaluate the psychometric properties of the Brazilian Portuguese version of the Po...

Sublethal abamectin exposure alters intraguild predation and population structure of predatory mites

Abstract Chemical contaminants can disrupt predator-prey dynamics in agroecosystems, particularly through intraguild predation (IGP), a key interaction influencing population structure and dynamics. The objective of this study was to investigate intraguild predation between Ambly...

Computational Design of Three-Dimensional Nitrogenated Holey Graphene Structures with Phase-Dependent Optoelectronic Properties

Abstract In this work, we propose and comprehensively characterize two novel three-dimensional nitrogenated holey graphene (3D-NHG) structures, designated as the α and β phases. These architectures are predicted through a computational protocol based on the controlled compression...