Universidad Nacional de Cuyo

Weaker Coherence, Weaker Reciprocity: Comparing the Semantic and Social Organization of Moltbook and Reddit

Large language models enable the creation of autonomous agents that interact in social environments, raising the question of whether agent-based platforms reproduce the organizational properties of human social networks. We compare Moltbook, a social network populated by AI agent...

Short-lived halogen sources and chemistry in the Community Earth System Model v2 (CESM2-SLH)

The implementation of short-lived halogen (SLH) sources and atmospheric chemistry in the Community Earth System Model v1 (CESM1) allowed to study the influence of SLH chemistry on the oxidative capacity of the atmosphere and, consequently, the Earth's climate. In this manuscript,...

Left-right asymmetry in the breast TME is associated with distinct bioelectric and epigenetic tumor features

Breast cancer heterogeneity is shaped not only by intrinsic tumor properties but by the surrounding microenvironment (TME). Here we report a left–right (L–R) asymmetry in the breast TME associated to tumor features. Bioinformatic analysis of TCGA RNA-seq and histological data rev...

Alpha-N-acetylglucosaminidase (NAGLU) inactivation causes morphological damage to the ultrastructural appearance of epididymal mononuclear phagocytes (eMPs) and epithelial cells of the epididymis in adult mice

Heparan sulfate (HS) a glycosaminoglycan family of carbohydrates, is covalently attached to core proteins forming heparan sulfate proteoglycans (HSPGs) which are found on the surface of cells. Following endocytosis, HSPGs are degraded within lysosomes by several enzymes, includin...

BDF6 Deficiency Severely Compromises Intracellular Amastigote Development and Infectivity of Trypanosoma cruzi

Abstract Trypanosoma cruzi, the causative agent of Chagas disease, relies on complex gene regulatory mechanisms to adapt to its diverse host environments. In recent years, it has been established that epigenetics plays an essential role in these mechanisms via the regulation of c...

Interlaminar Contralateral Endoscopic Foraminotomy Reduces Postoperative Dysesthesia in Patients With Degenerative Lumbar Deformity: A Multicenter Comparative Cohort Study

Study Design Retrospective-prospective multicenter comparative cohort study. Objectives Postoperative dysesthesia (POD) is a recognized complication of transforaminal endoscopic lumbar surgery, with reported rates up to 21.5%. Degenerative lumbar deformity may amplify this risk t...

Environmental associations and spatial segregation among coexisting Pogonomyrmex harvester ant species in the central Monte desert (Argentina)

Abstract Background Ant communities are widely considered to be structured by interspecific competition. Seed-harvesting ants are dominant granivores in drylands, and their colony locations influence their spatio-temporal effect on plant communities. Three closely related species...

A pair of duplicated SOC1 genes, DcSOC1-1 and DcSOC1-2, control vernalization requirement in carrot

Abstract Background Carrot vernalization requirement (VR), the amount of cold exposure needed for plants to become vernalized, strongly influences geographical adaptation of the crop and many agricultural practices, and this trait defines annual vs. biennial cultivars. Despite it...

Plastome convergence across endoparasitic plant lineages: genome reduction, high AT bias, elevated substitution rates, and functional persistence in Mitrastemon yamamotoi

In heterotrophic plants, the loss of photosynthesis is often associated with plastid genome (ptDNA) reduction, although the extent of genome decay varies widely among lineages and may culminate in complete genome loss. Of the multiple transitions to heterotrophy among angiosperms...