Unidad de Investigación en cuidados y servicios de salud (Investén-isciii)

Standards for practical management of drug hypersensitivity reactions to intravenous drugs and proactive early allergy involvement before referral: A WAO Statement

Hypersensitivity reactions to intravenous therapies—including antibiotics, chemotherapeutics, biologics, anesthesia agents, and contrast media—pose significant challenges in acute care settings. These reactions often occur outside the purview of allergy specialists, leading to de...

Effects of Physical Activity Interventions on Cognitive Flexibility in Children with ADHD: A Systematic Review

Background: Attention Deficit Hyperactivity Disorder (ADHD) is associated with impairments in executive functions, particularly cognitive flexibility, which may negatively affect academic performance, behavioral regulation, and daily adaptation in children. Physical activity has...

Evolution of functional and mental status and quality of life in people aged 75 years and over after the COVID-19 pandemic in Spain: a prospective cohort study

The COVID-19 pandemic has had significant health and psychosocial consequences in the older adults. However, there is little community-based evidence that clearly distinguishes the effect attributable to SARS-CoV-2 infection to be differentiated from the contextual impact of the...

Exploring Nursing Team Perceptions of Sleep in Critically Ill Pediatric Patients: A Mixed-Methods Study

Objective: To explore nursing team perceptions of sleep and sleep-disrupting factors in critically ill pediatric patients. Methodology: Convergent mixed-methods study comprising an exploratory qualitative and descriptive cross-sectional quantitative. For the qualitative component...

Barriers and facilitators to advance care planning implementation: a qualitative interprofessional study in the Spanish public health and social care system

Advance Care Planning (ACP) is essential for improving the quality of end-of-life care. Despite having a well-established legal framework, the implementation of ACP in Spain is limited and largely bureaucratic. The existing literature has primarily focused on knowledge deficits a...