UMass Memorial Medical Center

Social Risk Screening and Referrals in the Pediatric Inpatient Setting

BACKGROUND/OBJECTIVES: Many professional organizations recently recommended inpatient screening for social risks. Although prior studies have explored social risk screening rates in children's hospitals, many excluded community hospitals and lacked detail on screening practices....

Comparative Effectiveness of Phenobarbital vs Diazepam for Alcohol Withdrawal Syndrome

Importance Phenobarbital use for alcohol withdrawal syndrome is increasing, but its effectiveness and safety have largely been compared with lorazepam rather than against more pharmacokinetically similar long-acting, self-tapering benzodiazepines such as diazepam. Objective To em...

Epidemiology and Oncologic Patterns of Cervical Spine Metastases and Primary Tumors

STUDY DESIGN: Narrative review. OBJECTIVE: To summarize the epidemiology and oncologic patterns of metastatic and primary cervical spine tumors and evaluate the classification systems, instability assessments, cord compression frameworks, and prognostic tools used in their manage...

The ICG-Foley: A Novel Indocyanine Green-Coated Foley Catheter for Enhanced Anatomic Identification During Robot-Assisted Laparoscopic Prostatectomy

Background: Precise identification of the bladder neck and urethra during robot-assisted laparoscopic prostatectomy (RALP) is critical for continence preservation but remains challenging, particularly during the Retzius-sparing approach. Objective: To describe a novel indocyanine...

Artificial Intelligence in Counseling and Counseling Psychology: A Counselor-Led Framework for Ethical Practice & Training

As generative artificial intelligence (AI) tools like ChatGPT become increasingly accessible, counseling psychologists are exploring their potential use in clinical practice, often without clear guidance or ethical frameworks. This paper presents a counselor-led model for integra...

Modeling uncertainty in performance validity testing with Bayesian logistic regression

Objective: The aggregation of multiple performance validity tests (PVTs) into a summary validity determination is an established challenge in neuropsychology. The standard dichotomous accumulation approach relies upon binary recoding of continuous PVT scores and yields ambiguous...

Emergency department diagnosis and management of acetaminophen or salicylate toxicity.

Acetaminophen and salicylate are among the most widely used nonprescription analgesics and are common causes of toxic medication overdose. Diagnostic and management approaches differ depending on whether toxicity results from a single acute ingestion or chronic supratherapeutic u...

Quantitative computed tomography improves prediction of survival across ILD subtypes

Background Quantitative computed tomography (CT) methods are recognized as valuable tools for risk stratification in fibrotic interstitial lung disease (ILD). Data-driven textural analysis (DTA) is one such approach that correlates with worse lung function and shorter survival in...

JNK and p53 cause human and mouse β cell death during excessive unfolded protein response

Endoplasmic reticulum (ER) stress contributes to β cell death in both Type 1 and Type 2 diabetes (T1D and T2D). However, the molecular mechanisms driving β cell death during ER stress remain insufficiently defined, limiting development of protective therapies. GRP78, an ER chaper...