UC Irvine Health

Promoting arm movement practice with a novel wheelchair armrest early after stroke: a randomized controlled trial

Abstract Background Chronic upper extremity (UE) impairment is common after stroke. This study aimed to evaluate both the feasibility and preliminary clinical effects of Boost, a novel wheelchair-mounted rehabilitation device designed to assist individuals in UE motor recovery du...

Safety and financial analysis of outpatient HyperCVAD arm A administration for acute lymphoblastic leukemia

IntroductionOur institution transitioned the administration of hyperCVAD arm A to the outpatient setting via an Inpatient/Outpatient (IPOP) program. This study aims to evaluate the safety and financial impact of administering hyperCVAD arm A in the outpatient setting.DesignRetros...

Console-Associated Surgical Workflow Performance in Vitreoretinal Surgery: A Comparative Time-and-Motion Study of UNITY VCS and CONSTELLATION Vision Systems

Vitreoretinal operating rooms face increasing challenges, including workforce shortages and growing patient demand from aging populations. This comparative time-and-motion study assessed if the UNITY® Vitreoretinal Cataract System (UNITY VCS) was associated with differences in co...

Surgical considerations in post–programmed cell death-1 therapy for cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cSCC) can present as advanced disease requiring systemic therapy. Programmed cell death-1 (PD-1) inhibitors such as cemiplimab enable significant tumor regression. We report a patient with advanced cSCC who achieved near-complete remission after...

Heterogeneous Individual Valuations of a Mild Climate

Abstract This paper explores heterogeneous individual valuations of an important amenity, climate mildness, using a traditional Rosen-Roback empirical framework. It does so by including interaction terms between the amenity and worker characteristics in an hedonic wage regression...

Duration of Therapeutic Hypothermia After Out-of-Hospital Cardiac Arrest

Importance Therapeutic hypothermia is widely used for neuroprotection following cardiac arrest, but clinical trials have not consistently demonstrated improved neurological outcomes, and the optimal duration of cooling remains uncertain. Objective To determine the duration of the...

Decolonization vs Enhanced Cleaning for Multidrug-Resistant Organism Reduction in Nursing Homes

Importance Universal decolonization and enhanced cleaning are strategies to prevent multidrug-resistant organism (MDRO) transmission. Whether their associations with MDRO burden are overlapping, additive, or synergistic remains unknown. Objective To evaluate independent and combi...